What are the barriers to participation in a neuromodulation pilot trial for aphasia after stroke?
ABSTRACT Purpose Aphasia is a common and debilitating manifestation of stroke. Transcranial electrical stimulation uses low-intensity electric currents to induce changes in neuronal activity. Recent evidence suggests that noninvasive techniques can be a valuable rehabilitation tool for patients wit...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Fonoaudiologia
2021-07-01
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| Series: | CoDAS |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2317-17822021000400502&tlng=en |
| _version_ | 1798014970969980928 |
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| author | Mariana Lopes Andreoli Juli Thomaz de Souza Priscila Watson Ribeiro Rafael Dalle Molle da Costa Taís Regina da Silva Fernanda Cristina Winckler Gabriel Pinheiro Modolo Karen Fernanda Alves Pedro Tadao Hamamoto Filho Rafael Delascio Garcia Luiz Eduardo Gomes Garcia Betting Silmeia Garcia Zanati Bazan Rodrigo Bazan Gustavo José Luvizutto |
| author_facet | Mariana Lopes Andreoli Juli Thomaz de Souza Priscila Watson Ribeiro Rafael Dalle Molle da Costa Taís Regina da Silva Fernanda Cristina Winckler Gabriel Pinheiro Modolo Karen Fernanda Alves Pedro Tadao Hamamoto Filho Rafael Delascio Garcia Luiz Eduardo Gomes Garcia Betting Silmeia Garcia Zanati Bazan Rodrigo Bazan Gustavo José Luvizutto |
| author_sort | Mariana Lopes Andreoli |
| collection | DOAJ |
| description | ABSTRACT Purpose Aphasia is a common and debilitating manifestation of stroke. Transcranial electrical stimulation uses low-intensity electric currents to induce changes in neuronal activity. Recent evidence suggests that noninvasive techniques can be a valuable rehabilitation tool for patients with aphasia. However, it is difficult to recruit patients with aphasia for trials, and the reasons for this are not well understood. This study aimed to elucidate the main difficulties involved in patient’s recruitment and inclusion in a randomized clinical study of neuromodulation in aphasia. Methods We evaluated the reasons for the exclusion of patients in a pilot, randomized, double-blinded clinical trial in which patients diagnosed with motor aphasia after stroke were recruited from March to November 2018. A descriptive statistical analysis was performed. Results Only 12.9% (4) of patients with ischemic stroke were included in the clinical trial. A total of 87.1% (27) of the 31 recruited patients were excluded for various reasons including: sensory aphasia (32.2%), dysarthria (25.8%), spontaneous clinical recovery (16.1%), previous stroke (6.4%), and death or mutism (3.2%). Conclusion The presence of other types of aphasia, dysarthria, spontaneous recovery, deaths, and mutism were barriers to recruiting patients evidenced in this neuromodulation study. |
| first_indexed | 2024-04-11T15:26:44Z |
| format | Article |
| id | doaj.art-5a734427dba04508bc6500f79fc02770 |
| institution | Directory Open Access Journal |
| issn | 2317-1782 |
| language | English |
| last_indexed | 2024-04-11T15:26:44Z |
| publishDate | 2021-07-01 |
| publisher | Sociedade Brasileira de Fonoaudiologia |
| record_format | Article |
| series | CoDAS |
| spelling | doaj.art-5a734427dba04508bc6500f79fc027702022-12-22T04:16:14ZengSociedade Brasileira de FonoaudiologiaCoDAS2317-17822021-07-0133410.1590/2317-1782/20202020019What are the barriers to participation in a neuromodulation pilot trial for aphasia after stroke?Mariana Lopes Andreolihttps://orcid.org/0000-0003-1592-5973Juli Thomaz de Souzahttps://orcid.org/0000-0003-2227-7505Priscila Watson Ribeirohttps://orcid.org/0000-0002-6731-7593Rafael Dalle Molle da Costahttps://orcid.org/0000-0002-5977-8146Taís Regina da Silvahttps://orcid.org/0000-0002-4499-767XFernanda Cristina Wincklerhttps://orcid.org/0000-0002-7299-5612Gabriel Pinheiro Modolohttps://orcid.org/0000-0003-1057-5089Karen Fernanda Alveshttps://orcid.org/0000-0001-5209-3841Pedro Tadao Hamamoto Filhohttps://orcid.org/0000-0001-6436-9307Rafael Delascio Garciahttps://orcid.org/0000-0002-4967-6445Luiz Eduardo Gomes Garcia Bettinghttps://orcid.org/0000-0001-5680-2254Silmeia Garcia Zanati Bazanhttps://orcid.org/0000-0002-0607-8189Rodrigo Bazanhttps://orcid.org/0000-0003-3872-308XGustavo José Luvizuttohttps://orcid.org/0000-0002-6914-7225ABSTRACT Purpose Aphasia is a common and debilitating manifestation of stroke. Transcranial electrical stimulation uses low-intensity electric currents to induce changes in neuronal activity. Recent evidence suggests that noninvasive techniques can be a valuable rehabilitation tool for patients with aphasia. However, it is difficult to recruit patients with aphasia for trials, and the reasons for this are not well understood. This study aimed to elucidate the main difficulties involved in patient’s recruitment and inclusion in a randomized clinical study of neuromodulation in aphasia. Methods We evaluated the reasons for the exclusion of patients in a pilot, randomized, double-blinded clinical trial in which patients diagnosed with motor aphasia after stroke were recruited from March to November 2018. A descriptive statistical analysis was performed. Results Only 12.9% (4) of patients with ischemic stroke were included in the clinical trial. A total of 87.1% (27) of the 31 recruited patients were excluded for various reasons including: sensory aphasia (32.2%), dysarthria (25.8%), spontaneous clinical recovery (16.1%), previous stroke (6.4%), and death or mutism (3.2%). Conclusion The presence of other types of aphasia, dysarthria, spontaneous recovery, deaths, and mutism were barriers to recruiting patients evidenced in this neuromodulation study.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2317-17822021000400502&tlng=enStrokeAphasiaRehabilitationElectric StimulationBroca’s Area |
| spellingShingle | Mariana Lopes Andreoli Juli Thomaz de Souza Priscila Watson Ribeiro Rafael Dalle Molle da Costa Taís Regina da Silva Fernanda Cristina Winckler Gabriel Pinheiro Modolo Karen Fernanda Alves Pedro Tadao Hamamoto Filho Rafael Delascio Garcia Luiz Eduardo Gomes Garcia Betting Silmeia Garcia Zanati Bazan Rodrigo Bazan Gustavo José Luvizutto What are the barriers to participation in a neuromodulation pilot trial for aphasia after stroke? CoDAS Stroke Aphasia Rehabilitation Electric Stimulation Broca’s Area |
| title | What are the barriers to participation in a neuromodulation pilot trial for aphasia after stroke? |
| title_full | What are the barriers to participation in a neuromodulation pilot trial for aphasia after stroke? |
| title_fullStr | What are the barriers to participation in a neuromodulation pilot trial for aphasia after stroke? |
| title_full_unstemmed | What are the barriers to participation in a neuromodulation pilot trial for aphasia after stroke? |
| title_short | What are the barriers to participation in a neuromodulation pilot trial for aphasia after stroke? |
| title_sort | what are the barriers to participation in a neuromodulation pilot trial for aphasia after stroke |
| topic | Stroke Aphasia Rehabilitation Electric Stimulation Broca’s Area |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2317-17822021000400502&tlng=en |
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