Aurora-A interacts with AP-2α and down regulates its transcription activity.

Aurora-A interacts with AP-2α and down regulates its transcription activity.

Aurora-A is a serine/threonine protein kinase and plays an important role in the control of mitotic progression. Dysregulated expression of Aurora-A impairs centrosome separation and maturation, which lead to disrupted cell cycle progression and tumorigenesis. However, the molecular mechanism by whi...

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Bibliographic Details
Main Authors:	Lihui Zou, Yimin Sun, Mingrong Wang, Qimin Zhan
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3148253?pdf=render

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