The Role of Visual Evoked Potentials in the Differential Diagnosis of Demyelinating Diseases
Objective: Demyelinating diseases are included in the differential diagnosis of non-specific white matter lesions (NSWMLs), which are incidentally detected by magnetic resonance imaging (MRI) of the brain. This study aimed to investigate the role of visual evoked potentials (VEPs) in the diagnosis o...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2021-12-01
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| Series: | Türk Nöroloji Dergisi |
| Subjects: | |
| Online Access: | https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-75010 |
| _version_ | 1797923077846204416 |
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| author | Nurhan Kaya Tutar Sami Ömerhoca Elif Söylemez Turgut Adatepe Nilüfer Kale |
| author_facet | Nurhan Kaya Tutar Sami Ömerhoca Elif Söylemez Turgut Adatepe Nilüfer Kale |
| author_sort | Nurhan Kaya Tutar |
| collection | DOAJ |
| description | Objective: Demyelinating diseases are included in the differential diagnosis of non-specific white matter lesions (NSWMLs), which are incidentally detected by magnetic resonance imaging (MRI) of the brain. This study aimed to investigate the role of visual evoked potentials (VEPs) in the diagnosis of patients with demyelinating diseases.
Materials and Methods: In this retrospective study, the VEPs performed in our electrophysiology laboratory between 2017 and 2018 were evaluated. One hundred and thirty-two patients with complete medical records were included in the study. After 2 years of follow-up, three groups were formed: 1st group: Demyelinating spectrum (multiple sclerosis, clinically isolated syndrome, radiologically isolated syndrome, and possible demyelinating disease); 2nd group: NSWMLs; and 3rd group (control): Subjects with normal neurological examination and neuroimaging after presenting with symptoms.
Results: The VEP findings demonstrated a significant latency prolongation and an amplitude reduction in the demyelinating disease group compared to the NSWMLs and control groups. The VEP parameters of the NSWMLs group did not differ from those of the control group.
Conclusion: Abnormalities in VEP suggest a demyelinating spectrum, whereas a normal VEP may suggest the absence of a demyelinating process. In cases where non-specific MRI findings cannot be supported by clinical data, a normal VEP diagnosis may help exclude demyelinating diseases. |
| first_indexed | 2024-04-10T14:41:29Z |
| format | Article |
| id | doaj.art-5a742403929c4f1da3ea197dc450c937 |
| institution | Directory Open Access Journal |
| issn | 1309-2545 |
| language | English |
| last_indexed | 2024-04-10T14:41:29Z |
| publishDate | 2021-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Nöroloji Dergisi |
| spelling | doaj.art-5a742403929c4f1da3ea197dc450c9372023-02-15T16:08:08ZengGalenos YayineviTürk Nöroloji Dergisi1309-25452021-12-0127436637010.4274/tnd.2021.75010The Role of Visual Evoked Potentials in the Differential Diagnosis of Demyelinating DiseasesNurhan Kaya Tutar0https://orcid.org/0000-0002-2713-4282Sami Ömerhoca1https://orcid.org/0000-0002-5899-1180Elif Söylemez2https://orcid.org/0000-0002-2936-7477Turgut Adatepe3https://orcid.org/0000-0001-6863-6820Nilüfer Kale4https://orcid.org/0000-0002-7994-6223University of Health Sciences Turkey, Istanbul Bagcilar Training and Research Hospital, Clinic of Neurology, Istanbul, TurkeyUniversity of Health Sciences Turkey, Istanbul Bagcilar Training and Research Hospital, Clinic of Neurology, Istanbul, TurkeyUniversity of Health Sciences Turkey, Istanbul Bagcilar Training and Research Hospital, Clinic of Neurology, Istanbul, TurkeyUniversity of Health Sciences Turkey, Istanbul Bagcilar Training and Research Hospital, Clinic of Neurology, Istanbul, TurkeyUniversity of Health Sciences Turkey, Istanbul Bagcilar Training and Research Hospital, Clinic of Neurology, Istanbul, TurkeyObjective: Demyelinating diseases are included in the differential diagnosis of non-specific white matter lesions (NSWMLs), which are incidentally detected by magnetic resonance imaging (MRI) of the brain. This study aimed to investigate the role of visual evoked potentials (VEPs) in the diagnosis of patients with demyelinating diseases. Materials and Methods: In this retrospective study, the VEPs performed in our electrophysiology laboratory between 2017 and 2018 were evaluated. One hundred and thirty-two patients with complete medical records were included in the study. After 2 years of follow-up, three groups were formed: 1st group: Demyelinating spectrum (multiple sclerosis, clinically isolated syndrome, radiologically isolated syndrome, and possible demyelinating disease); 2nd group: NSWMLs; and 3rd group (control): Subjects with normal neurological examination and neuroimaging after presenting with symptoms. Results: The VEP findings demonstrated a significant latency prolongation and an amplitude reduction in the demyelinating disease group compared to the NSWMLs and control groups. The VEP parameters of the NSWMLs group did not differ from those of the control group. Conclusion: Abnormalities in VEP suggest a demyelinating spectrum, whereas a normal VEP may suggest the absence of a demyelinating process. In cases where non-specific MRI findings cannot be supported by clinical data, a normal VEP diagnosis may help exclude demyelinating diseases.https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-75010visual evoked potentialsnon-specific white matter lesionsdemyelinating diseasemultiple sclerosis |
| spellingShingle | Nurhan Kaya Tutar Sami Ömerhoca Elif Söylemez Turgut Adatepe Nilüfer Kale The Role of Visual Evoked Potentials in the Differential Diagnosis of Demyelinating Diseases Türk Nöroloji Dergisi visual evoked potentials non-specific white matter lesions demyelinating disease multiple sclerosis |
| title | The Role of Visual Evoked Potentials in the Differential Diagnosis of Demyelinating Diseases |
| title_full | The Role of Visual Evoked Potentials in the Differential Diagnosis of Demyelinating Diseases |
| title_fullStr | The Role of Visual Evoked Potentials in the Differential Diagnosis of Demyelinating Diseases |
| title_full_unstemmed | The Role of Visual Evoked Potentials in the Differential Diagnosis of Demyelinating Diseases |
| title_short | The Role of Visual Evoked Potentials in the Differential Diagnosis of Demyelinating Diseases |
| title_sort | role of visual evoked potentials in the differential diagnosis of demyelinating diseases |
| topic | visual evoked potentials non-specific white matter lesions demyelinating disease multiple sclerosis |
| url | https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-75010 |
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