Gene expression promoted by the SV40 DNA targeting sequence and the hypoxia-responsive element under normoxia and hypoxia

Gene expression promoted by the SV40 DNA targeting sequence and the hypoxia-responsive element under normoxia and hypoxia

The main objective of the present study was to find suitable DNA-targeting sequences (DTS) for the construction of plasmid vectors to be used to treat ischemic diseases. The well-known Simian virus 40 nuclear DTS (SV40-DTS) and hypoxia-responsive element (HRE) sequences were used to construct plasmi...

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Bibliographic Details
Main Authors:	C.B. Sacramento, J.Z. Moraes, P.M.A. Denapolis, S.W. Han
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2010-08-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	SV40-DTS Hypoxia-responsive element Transfection efficiency Normoxia Hypoxia Ischemic diseases
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000800005

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