DNA damage repair profiling of esophageal squamous cell carcinoma uncovers clinically relevant molecular subtypes with distinct prognoses and therapeutic vulnerabilitiesResearch in context

DNA damage repair profiling of esophageal squamous cell carcinoma uncovers clinically relevant molecular subtypes with distinct prognoses and therapeutic vulnerabilitiesResearch in context

Summary: Background: DNA damage repair (DDR) is a critical process that maintains genomic integrity and plays essential roles at both the cellular and organismic levels. Here, we aimed to characterize the DDR profiling of esophageal squamous cell carcinoma (ESCC), investigate the prognostic value o...

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Bibliographic Details
Main Authors: Ning Zhao, Zicheng Zhang, Qiang Wang, Lin Li, Zichao Wei, Hongyan Chen, Meng Zhou, Zhihua Liu, Jianzhong Su
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:EBioMedicine
Subjects:
DNA damage repair
Esophageal squamous cell carcinoma
Immunotherapeutic targets
Tumor microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423003675

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http://www.sciencedirect.com/science/article/pii/S2352396423003675

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