Rh(III)‐Catalyzed C‐2 Alkylation of Indoles followed by a Post‐Synthetic Modification via the Ugi Reaction

Rh(III)‐Catalyzed C‐2 Alkylation of Indoles followed by a Post‐Synthetic Modification via the Ugi Reaction

Abstract Indole derivatives substituted at the C‐2 position have shown important biological activities. Due to these properties, several methods have been described for the preparation of structurally diverse indoles. In this work, we have synthesized highly functionalized indole derivatives via Rh(...

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Bibliographic Details
Main Authors: Marcelo Augusto Pereira Januário, Demetrius P. deSouza, Prof. Dr. Julio Zukerman‐Schpector, Prof. Dr. Arlene G. Corrêa
Format: Article
Language:English
Published: Wiley-VCH 2023-06-01
Series:ChemistryOpen
Subjects:
CH activation
indole
Rh catalysis
nitroalkane reduction
Ugi reaction
Online Access:https://doi.org/10.1002/open.202300070

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