Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review
INTRODUCTION: The use of statins in hemodialysis patients is a topic of ongoing research and debate. Patients with chronic kidney disease on hemodialysis constitute a large proportion of patients treated in the vascular surgery field. Clinical data of the protective statin effect on this group is s...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Portuguese |
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Sociedade Portuguesa de Angiologia e Cirurgia Vascular
2024-03-01
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| Series: | Angiologia e Cirurgia Vascular |
| Subjects: | |
| Online Access: | https://acvjournal.com/index.php/acv/article/view/552 |
| _version_ | 1797279321377734656 |
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| author | Celso Nunes Juliana Sousa Vânia Oliveira Eduardo Silva Leonor Baldaia Miguel Silva Luis Orelhas Manuel Fonseca |
| author_facet | Celso Nunes Juliana Sousa Vânia Oliveira Eduardo Silva Leonor Baldaia Miguel Silva Luis Orelhas Manuel Fonseca |
| author_sort | Celso Nunes |
| collection | DOAJ |
| description |
INTRODUCTION: The use of statins in hemodialysis patients is a topic of ongoing research and debate. Patients with chronic kidney disease on hemodialysis constitute a large proportion of patients treated in the vascular surgery field. Clinical data of the protective statin effect on this group is scarce and conflicting results exist regarding cardiovascular, cerebrovascular and limb outcomes.
METHODS: We performed a thorough electronic search of the literature using PubMed and Embase databases to understand the relationship between statin effect and cardiovascular, limb outcomes and cerebrovascular outcomes. A narrative review was constructed, based on the obtained literature.
RESULTS: Although the use of statins in hemodialysis patients may provide cardiovascular benefits, the optimal dosage and safety profile of these medications in this population remain uncertain. A carefully evaluation of the risks and benefits of statins should be made based on each patient's specific requirements and circumstances.
CONCLUSION: The role of statins for patients with peripheral arterial disease who are on hemodialysis remains unclear. Further analyses should focus on this subgroup of dialysis patients, who are becoming more prevalent on the vascular surgery departments, allowing for an optimized treatment with better patient outcomes.
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| first_indexed | 2024-03-07T16:23:36Z |
| format | Article |
| id | doaj.art-5a835f4815f6467f86ac5d1c34c5f625 |
| institution | Directory Open Access Journal |
| issn | 1646-706X 2183-0096 |
| language | Portuguese |
| last_indexed | 2024-03-07T16:23:36Z |
| publishDate | 2024-03-01 |
| publisher | Sociedade Portuguesa de Angiologia e Cirurgia Vascular |
| record_format | Article |
| series | Angiologia e Cirurgia Vascular |
| spelling | doaj.art-5a835f4815f6467f86ac5d1c34c5f6252024-03-03T23:40:55ZporSociedade Portuguesa de Angiologia e Cirurgia VascularAngiologia e Cirurgia Vascular1646-706X2183-00962024-03-0119410.48750/acv.552Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative reviewCelso Nunes0Juliana Sousa1Vânia Oliveira2Eduardo Silva3Leonor Baldaia4Miguel Silva5Luis Orelhas6Manuel Fonseca7Angiology and Vascular Surgery Department, Centro Hospitalar e Universitário de Coimbra, PortugalAngiology and Vascular Surgery Department, Centro Hospitalar e Universitário de Coimbra, PortugalAngiology and Vascular Surgery Department, Centro Hospitalar e Universitário de Coimbra, PortugalAngiology and Vascular Surgery Department, Centro Hospitalar e Universitário de Coimbra, PortugalAngiology and Vascular Surgery Department, Centro Hospitalar e Universitário de Coimbra, PortugalAngiology and Vascular Surgery Department, Centro Hospitalar e Universitário de Coimbra, PortugalAngiology and Vascular Surgery Department, Centro Hospitalar e Universitário de Coimbra, PortugalAngiology and Vascular Surgery Department, Centro Hospitalar e Universitário de Coimbra, Portugal INTRODUCTION: The use of statins in hemodialysis patients is a topic of ongoing research and debate. Patients with chronic kidney disease on hemodialysis constitute a large proportion of patients treated in the vascular surgery field. Clinical data of the protective statin effect on this group is scarce and conflicting results exist regarding cardiovascular, cerebrovascular and limb outcomes. METHODS: We performed a thorough electronic search of the literature using PubMed and Embase databases to understand the relationship between statin effect and cardiovascular, limb outcomes and cerebrovascular outcomes. A narrative review was constructed, based on the obtained literature. RESULTS: Although the use of statins in hemodialysis patients may provide cardiovascular benefits, the optimal dosage and safety profile of these medications in this population remain uncertain. A carefully evaluation of the risks and benefits of statins should be made based on each patient's specific requirements and circumstances. CONCLUSION: The role of statins for patients with peripheral arterial disease who are on hemodialysis remains unclear. Further analyses should focus on this subgroup of dialysis patients, who are becoming more prevalent on the vascular surgery departments, allowing for an optimized treatment with better patient outcomes. https://acvjournal.com/index.php/acv/article/view/552StatinHemodialysisperipheral arterial diseasepatient outcomes |
| spellingShingle | Celso Nunes Juliana Sousa Vânia Oliveira Eduardo Silva Leonor Baldaia Miguel Silva Luis Orelhas Manuel Fonseca Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review Angiologia e Cirurgia Vascular Statin Hemodialysis peripheral arterial disease patient outcomes |
| title | Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review |
| title_full | Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review |
| title_fullStr | Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review |
| title_full_unstemmed | Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review |
| title_short | Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review |
| title_sort | effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease a narrative review |
| topic | Statin Hemodialysis peripheral arterial disease patient outcomes |
| url | https://acvjournal.com/index.php/acv/article/view/552 |
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