Postoperative Changes in Systemic Immune Tolerance Following Major Oncologic versus Minor Maxillofacial Surgery

Postoperative Changes in Systemic Immune Tolerance Following Major Oncologic versus Minor Maxillofacial Surgery

Background: There is increasing evidence of the benefits of adjuvant and neoadjuvant immunotherapy in the treatment of solid malignancies like oral squamous cell carcinoma (OSCC). To optimize (neo-)adjuvant treatment, the systemic immunomodulatory effects of tumor surgery itself need to be considere...

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Bibliographic Details
Main Authors: Leah Trumet, Jutta Ries, Philip Sobl, Niclas Ivenz, Falk Wehrhan, Rainer Lutz, Marco Kesting, Manuel Weber
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cancers
Subjects:
immune tolerance
IL-6
IL-10
FOXP3
PD-L1
immunotherapy
Online Access:https://www.mdpi.com/2072-6694/15/15/3755

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