Susceptibility to Fluconazole and Voriconazole in Candida Strains Isolated from Blood Culture by Disk Diffusion Method. Maracaibo, Venezuela
To determine the susceptibility of Candida strains isolated from blood cultures in Maracaibo, Venezuela, 78 strains obtained from hospitalized patients in different services of the autonomous Maracaibo University Hospital, Venezuela, were studied. Chromogenic Medium Brilliance Candida Agar and Vitek...
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| Format: | Article |
| Language: | English |
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Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales
2011-02-01
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| Series: | Kasmera |
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| Online Access: | https://produccioncientificaluz.org/index.php/kasmera/article/view/4881 |
| _version_ | 1827838888085815296 |
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| author | Armindo Perozo Belinda Calvo Luzmila Mesa Maritza Pineda |
| author_facet | Armindo Perozo Belinda Calvo Luzmila Mesa Maritza Pineda |
| author_sort | Armindo Perozo |
| collection | DOAJ |
| description | To determine the susceptibility of Candida strains isolated from blood cultures in Maracaibo, Venezuela, 78 strains obtained from hospitalized patients in different services of the autonomous Maracaibo University Hospital, Venezuela, were studied. Chromogenic Medium Brilliance Candida Agar and Vitek-YBC were used for species identification. In addition, cultures were assessed using the traditional identification method. Susceptibility was determined by the diffusion method with fluconazole and voriconazole disks, according to the Clinical and Laboratory Standard Institute, Document M44-A2. Frequency of the Candida species was: C. parapsilosis 51.28%, C. tropicalis 15.38%, C. guilliermondii 11.54%, C. albicans 10.26% C. famata 6.41%, C. glabrata 3.85% and C. krusei 1.28%. Susceptibility was 96.15% and 100% for fluconazole and voriconazole, respectively. Three isolates identified as C. albicans, C. guilliermondii and C. krusei were resistant to fluconazole. These results suggest that fluconazole and voriconazole can be useful in the treatment of patients with candidemia; however, epidemiological surveillance and susceptibility pattern determination of Candida must be maintained. |
| first_indexed | 2024-03-12T07:12:09Z |
| format | Article |
| id | doaj.art-5a855bbd3aec43768b631b21d1a55a87 |
| institution | Directory Open Access Journal |
| issn | 0075-5222 2477-9628 |
| language | English |
| last_indexed | 2024-03-12T07:12:09Z |
| publishDate | 2011-02-01 |
| publisher | Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales |
| record_format | Article |
| series | Kasmera |
| spelling | doaj.art-5a855bbd3aec43768b631b21d1a55a872023-09-02T23:00:31ZengUniversidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y TropicalesKasmera0075-52222477-96282011-02-013921141224880Susceptibility to Fluconazole and Voriconazole in Candida Strains Isolated from Blood Culture by Disk Diffusion Method. Maracaibo, VenezuelaArmindo Perozo0Belinda Calvo1Luzmila Mesa2Maritza Pineda3Escuela de Bioanálisis, Facultad de Medicina. Centro de Referencia Bacteriológica, Servicio Autónomo Hospital Universitario de Maracaibo. Venezuela.Departamento de Enfermedades Infecciosas. Servicio Autónomo Hospital Universitario de Maracaibo. Venezuela.Departamento de Microbiología, Escuela de Bioanálisis. Universidad del Zulia. VenezuelaDepartamento de Medicina Interna, Centro de Referencia Bacteriológica. Servicio Autónomo Hospital Universitario de Maracaibo. Venezuela. Escuela de Medicina. Universidad del Zulia. Venezuela.To determine the susceptibility of Candida strains isolated from blood cultures in Maracaibo, Venezuela, 78 strains obtained from hospitalized patients in different services of the autonomous Maracaibo University Hospital, Venezuela, were studied. Chromogenic Medium Brilliance Candida Agar and Vitek-YBC were used for species identification. In addition, cultures were assessed using the traditional identification method. Susceptibility was determined by the diffusion method with fluconazole and voriconazole disks, according to the Clinical and Laboratory Standard Institute, Document M44-A2. Frequency of the Candida species was: C. parapsilosis 51.28%, C. tropicalis 15.38%, C. guilliermondii 11.54%, C. albicans 10.26% C. famata 6.41%, C. glabrata 3.85% and C. krusei 1.28%. Susceptibility was 96.15% and 100% for fluconazole and voriconazole, respectively. Three isolates identified as C. albicans, C. guilliermondii and C. krusei were resistant to fluconazole. These results suggest that fluconazole and voriconazole can be useful in the treatment of patients with candidemia; however, epidemiological surveillance and susceptibility pattern determination of Candida must be maintained.https://produccioncientificaluz.org/index.php/kasmera/article/view/4881especies de candidacandidemiahemocultivosfluconazolvoriconazol |
| spellingShingle | Armindo Perozo Belinda Calvo Luzmila Mesa Maritza Pineda Susceptibility to Fluconazole and Voriconazole in Candida Strains Isolated from Blood Culture by Disk Diffusion Method. Maracaibo, Venezuela Kasmera especies de candida candidemia hemocultivos fluconazol voriconazol |
| title | Susceptibility to Fluconazole and Voriconazole in Candida Strains Isolated from Blood Culture by Disk Diffusion Method. Maracaibo, Venezuela |
| title_full | Susceptibility to Fluconazole and Voriconazole in Candida Strains Isolated from Blood Culture by Disk Diffusion Method. Maracaibo, Venezuela |
| title_fullStr | Susceptibility to Fluconazole and Voriconazole in Candida Strains Isolated from Blood Culture by Disk Diffusion Method. Maracaibo, Venezuela |
| title_full_unstemmed | Susceptibility to Fluconazole and Voriconazole in Candida Strains Isolated from Blood Culture by Disk Diffusion Method. Maracaibo, Venezuela |
| title_short | Susceptibility to Fluconazole and Voriconazole in Candida Strains Isolated from Blood Culture by Disk Diffusion Method. Maracaibo, Venezuela |
| title_sort | susceptibility to fluconazole and voriconazole in candida strains isolated from blood culture by disk diffusion method maracaibo venezuela |
| topic | especies de candida candidemia hemocultivos fluconazol voriconazol |
| url | https://produccioncientificaluz.org/index.php/kasmera/article/view/4881 |
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