Cheiro-oral-pedal syndrome of the pons and the role of imaging in diagnosis and management

The patient is a 58-year-old male who presented with chief complaints of right-sided numbness, tingling, and loss of temperature sensation in the upper and lower extremities. The patient’s symptoms began around the face and right corner of the mouth [maxillary/mandibular (V2/V3) distribution] before...

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Main Authors: Zachary I. Merhavy, Garrett D. Barfoot, Leah Dajani, Zainab Elmahmoud, Emmanuel Flores, Thomas C. Varkey
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2023-10-01
Series:Exploration of Medicine
Subjects:
Online Access:https://www.explorationpub.com/Journals/em/Article/1001174
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author Zachary I. Merhavy
Garrett D. Barfoot
Leah Dajani
Zainab Elmahmoud
Emmanuel Flores
Thomas C. Varkey
author_facet Zachary I. Merhavy
Garrett D. Barfoot
Leah Dajani
Zainab Elmahmoud
Emmanuel Flores
Thomas C. Varkey
author_sort Zachary I. Merhavy
collection DOAJ
description The patient is a 58-year-old male who presented with chief complaints of right-sided numbness, tingling, and loss of temperature sensation in the upper and lower extremities. The patient’s symptoms began around the face and right corner of the mouth [maxillary/mandibular (V2/V3) distribution] before descending to the arm, trunk, and followed by the lower leg and foot. His home medication regimen included lisinopril, atorvastatin, long and short-acting insulin, and amlodipine. During the interview, the patient admitted to abstinence from his medications. Upon examination, the patient was found to have a loss of hot and cold touch on the right side and expressed 2+ reflexes (brisk response; normal) on both upper and lower extremities. In the initial work-up of the patient, he received a computed tomography (CT) scan which demonstrated an area of potential ischemic infarct of one of the left sided pontine perforator arteries. Immediately at that time he was given a loading dose of 325 mg aspirin and started on 81 mg daily. Because of the patient’s symptoms and risk factors, he was hospitalized for further additional work-up and eventually discharged on dual antiplatelet therapy. This case is intriguing as both neuroradiological reading and neurological examination helped with localization of the lesion and changing the treatment strategy of the patient. With a pontine perforator ischemic event, the harms of treatment with thrombolytics would have outweighed the benefits. This interprofessional work between neuroradiology, internal medicine, and neurology ensured that the patient received the best care for his specific ailments.
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spelling doaj.art-5a85c1d78a5a44d29294f6ec8598924c2023-11-01T05:23:12ZengOpen Exploration Publishing Inc.Exploration of Medicine2692-31062023-10-014573974610.37349/emed.2023.00174Cheiro-oral-pedal syndrome of the pons and the role of imaging in diagnosis and managementZachary I. Merhavy0https://orcid.org/0000-0002-8860-1980Garrett D. Barfoot1https://orcid.org/0009-0002-9444-6670Leah Dajani2Zainab Elmahmoud3Emmanuel Flores4Thomas C. Varkey5https://orcid.org/0000-0002-3586-2909Department of Veterans Affairs, Veterans Health Administration, Phoenix, AZ 85012, USA; Department of Medical Sciences, Ross University School of Medicine, Bridgetown BB11093, Barbados; Department of Neurology, University of Arizona College of Medicine, Phoenix, AZ 85724, USADepartment of Veterans Affairs, Veterans Health Administration, Phoenix, AZ 85012, USA; Department of Medical Sciences, Ross University School of Medicine, Bridgetown BB11093, BarbadosDepartment of Veterans Affairs, Veterans Health Administration, Phoenix, AZ 85012, USA; Department of Medical Sciences, Ross University School of Medicine, Bridgetown BB11093, BarbadosDepartment of Veterans Affairs, Veterans Health Administration, Phoenix, AZ 85012, USA; Department of Medical Sciences, Ross University School of Medicine, Bridgetown BB11093, BarbadosDepartment of Veterans Affairs, Veterans Health Administration, Phoenix, AZ 85012, USA; Department of Medical Sciences, Ross University School of Medicine, Bridgetown BB11093, BarbadosDepartment of Veterans Affairs, Veterans Health Administration, Phoenix, AZ 85012, USA; Department of Neurology, University of Arizona College of Medicine, Phoenix, AZ 85724, USA; Colangelo College of Business, Grand Canyon University, Phoenix, AZ 85017, USAThe patient is a 58-year-old male who presented with chief complaints of right-sided numbness, tingling, and loss of temperature sensation in the upper and lower extremities. The patient’s symptoms began around the face and right corner of the mouth [maxillary/mandibular (V2/V3) distribution] before descending to the arm, trunk, and followed by the lower leg and foot. His home medication regimen included lisinopril, atorvastatin, long and short-acting insulin, and amlodipine. During the interview, the patient admitted to abstinence from his medications. Upon examination, the patient was found to have a loss of hot and cold touch on the right side and expressed 2+ reflexes (brisk response; normal) on both upper and lower extremities. In the initial work-up of the patient, he received a computed tomography (CT) scan which demonstrated an area of potential ischemic infarct of one of the left sided pontine perforator arteries. Immediately at that time he was given a loading dose of 325 mg aspirin and started on 81 mg daily. Because of the patient’s symptoms and risk factors, he was hospitalized for further additional work-up and eventually discharged on dual antiplatelet therapy. This case is intriguing as both neuroradiological reading and neurological examination helped with localization of the lesion and changing the treatment strategy of the patient. With a pontine perforator ischemic event, the harms of treatment with thrombolytics would have outweighed the benefits. This interprofessional work between neuroradiology, internal medicine, and neurology ensured that the patient received the best care for his specific ailments.https://www.explorationpub.com/Journals/em/Article/1001174cheiro-oral-pedalneurologyradiologyneuroradiologyimaging
spellingShingle Zachary I. Merhavy
Garrett D. Barfoot
Leah Dajani
Zainab Elmahmoud
Emmanuel Flores
Thomas C. Varkey
Cheiro-oral-pedal syndrome of the pons and the role of imaging in diagnosis and management
Exploration of Medicine
cheiro-oral-pedal
neurology
radiology
neuroradiology
imaging
title Cheiro-oral-pedal syndrome of the pons and the role of imaging in diagnosis and management
title_full Cheiro-oral-pedal syndrome of the pons and the role of imaging in diagnosis and management
title_fullStr Cheiro-oral-pedal syndrome of the pons and the role of imaging in diagnosis and management
title_full_unstemmed Cheiro-oral-pedal syndrome of the pons and the role of imaging in diagnosis and management
title_short Cheiro-oral-pedal syndrome of the pons and the role of imaging in diagnosis and management
title_sort cheiro oral pedal syndrome of the pons and the role of imaging in diagnosis and management
topic cheiro-oral-pedal
neurology
radiology
neuroradiology
imaging
url https://www.explorationpub.com/Journals/em/Article/1001174
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