Regioselective and Stereoselective Synthesis of Parthenolide Analogs by Acyl Nitroso-Ene Reaction and Their Biological Evaluation against <i>Mycobacterium tuberculosis</i>

Regioselective and Stereoselective Synthesis of Parthenolide Analogs by Acyl Nitroso-Ene Reaction and Their Biological Evaluation against <i>Mycobacterium tuberculosis</i>

Historically, natural products have played a major role in the development of antibiotics. Their complex chemical structures and high polarity give them advantages in the drug discovery process. In the broad range of natural products, sesquiterpene lactones are interesting compounds because of their...

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Bibliographic Details
Main Authors: Bruna Gioia, Francesca Ruggieri, Alexandre Biela, Valérie Landry, Pascal Roussel, Catherine Piveteau, Florence Leroux, Ruben C. Hartkoorn, Nicolas Willand
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
natural products
semisynthesis
<i>Mycobacterium tuberculosis</i>
Online Access:https://www.mdpi.com/1422-0067/24/24/17395

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