High-resolution micro-CT for 3D infarct characterization and segmentation in mice stroke models
Abstract Characterization of brain infarct lesions in rodent models of stroke is crucial to assess stroke pathophysiology and therapy outcome. Until recently, the analysis of brain lesions was performed using two techniques: (1) histological methods, such as TTC (Triphenyltetrazolium chloride), a ti...
Main Authors: | Raquel Pinto, Jan Matula, Maria Gomez-Lazaro, Mafalda Sousa, Andrea Lobo, Tomas Zikmund, Jozef Kaiser, João R. Gomes |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-10-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-21494-9 |
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