Analysis of the H-Ras mobility pattern in vivo shows cellular heterogeneity inside epidermal tissue

Analysis of the H-Ras mobility pattern in vivo shows cellular heterogeneity inside epidermal tissue

Developments in single-molecule microscopy (SMM) have enabled imaging individual proteins in biological systems, focusing on the analysis of protein mobility patterns inside cultured cells. In the present study, SMM was applied in vivo, using the zebrafish embryo model. We studied dynamics of the me...

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Bibliographic Details
Main Authors: Radoslaw J. Gora, Babette de Jong, Patrick van Hage, Mary Ann Rhiemus, Fjodor van Steenis, John van Noort, Thomas Schmidt, Marcel J. M. Schaaf
Format: Article
Language:English
Published: The Company of Biologists 2022-02-01
Series:Disease Models & Mechanisms
Subjects:
h-ras
zebrafish
single-molecule microscopy
total internal reflection fluorescence microscopy
membrane microdomains
diffusion
Online Access:http://dmm.biologists.org/content/15/2/dmm049099

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