Birthweight trends and their explanatory factors in Hungary between 1999 and 2018: an analysis of the Hungarian Tauffer registry
Abstract Background The increasing birthweight trend stopped and even reversed in several high income countries in the last 20 years, however the reason for these changes is not well characterized. We aimed to describe birthweight trends of term deliveries in Hungary between 1999 and 2018 and to inv...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2024-04-01
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| Series: | Reproductive Health |
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| Online Access: | https://doi.org/10.1186/s12978-024-01787-0 |
| _version_ | 1797209278199627776 |
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| author | László Zsirai Attila Kun Gergely Á. Visolyi Márk M. Svébis Beatrix A. Domján Ádám Tabák |
| author_facet | László Zsirai Attila Kun Gergely Á. Visolyi Márk M. Svébis Beatrix A. Domján Ádám Tabák |
| author_sort | László Zsirai |
| collection | DOAJ |
| description | Abstract Background The increasing birthweight trend stopped and even reversed in several high income countries in the last 20 years, however the reason for these changes is not well characterized. We aimed to describe birthweight trends of term deliveries in Hungary between 1999 and 2018 and to investigate potential maternal and foetal variables that could drive these changes. Methods We analysed data from the Hungarian Tauffer registry, a compulsory anonymized data collection of each delivery. We included all singleton term deliveries in 1999–2018 (n = 1,591,932). We modelled birthweight trends separately in 1999–2008 and 2008–2018 in hierarchical multiple linear regression models adjusted for calendar year, newborn sex, maternal age, gestational age at delivery, and other important determinants. Results Median birthweights increased from 3250/3400 g (girl/boy) to 3300/3440 g from 1999 to 2008 and decreased to 3260/3400 g in 2018. When we adjusted for gestational age at delivery the increase in the first period became more pronounced (5.4 g/year). During the second period, similar adjustment substantially decreased the rate of decline from 2.5 to 1.4 g/year. Further adjustment for maternal age halved the rate of increase to 2.4 g/year in the first period. During the second period, adjustment for maternal age had little effect on the estimate. Conclusions Our findings of an increasing birthweight trend (mostly related to the aging of the mothers) in 1999–2008 may forecast an increased risk of cardiometabolic diseases in offsprings born in this period. In contrast, the decreasing birthweight trends after 2008 may reflect some beneficial effects on perinatal morbidity. However, the long-term effect cannot be predicted, as the trend is mostly explained by the shorter pregnancies. |
| first_indexed | 2024-04-24T09:52:09Z |
| format | Article |
| id | doaj.art-5a90efe347fd43058e84f3141ccf1fd6 |
| institution | Directory Open Access Journal |
| issn | 1742-4755 |
| language | English |
| last_indexed | 2024-04-24T09:52:09Z |
| publishDate | 2024-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Reproductive Health |
| spelling | doaj.art-5a90efe347fd43058e84f3141ccf1fd62024-04-14T11:18:16ZengBMCReproductive Health1742-47552024-04-0121111310.1186/s12978-024-01787-0Birthweight trends and their explanatory factors in Hungary between 1999 and 2018: an analysis of the Hungarian Tauffer registryLászló Zsirai0Attila Kun1Gergely Á. Visolyi2Márk M. Svébis3Beatrix A. Domján4Ádám Tabák5Department of Gynaecology and Family Planning, Istenhegyi GeneDiagnostic CenterDepartment of Obstetrics and Gynaecology, Tolna County Balassa János HospitalKároly Rácz School of PhD Studies, Semmelweis UniversityKároly Rácz School of PhD Studies, Semmelweis UniversityDepartment of Internal Medicine and Oncology, Semmelweis University Faculty of MedicineDepartment of Internal Medicine and Oncology, Semmelweis University Faculty of MedicineAbstract Background The increasing birthweight trend stopped and even reversed in several high income countries in the last 20 years, however the reason for these changes is not well characterized. We aimed to describe birthweight trends of term deliveries in Hungary between 1999 and 2018 and to investigate potential maternal and foetal variables that could drive these changes. Methods We analysed data from the Hungarian Tauffer registry, a compulsory anonymized data collection of each delivery. We included all singleton term deliveries in 1999–2018 (n = 1,591,932). We modelled birthweight trends separately in 1999–2008 and 2008–2018 in hierarchical multiple linear regression models adjusted for calendar year, newborn sex, maternal age, gestational age at delivery, and other important determinants. Results Median birthweights increased from 3250/3400 g (girl/boy) to 3300/3440 g from 1999 to 2008 and decreased to 3260/3400 g in 2018. When we adjusted for gestational age at delivery the increase in the first period became more pronounced (5.4 g/year). During the second period, similar adjustment substantially decreased the rate of decline from 2.5 to 1.4 g/year. Further adjustment for maternal age halved the rate of increase to 2.4 g/year in the first period. During the second period, adjustment for maternal age had little effect on the estimate. Conclusions Our findings of an increasing birthweight trend (mostly related to the aging of the mothers) in 1999–2008 may forecast an increased risk of cardiometabolic diseases in offsprings born in this period. In contrast, the decreasing birthweight trends after 2008 may reflect some beneficial effects on perinatal morbidity. However, the long-term effect cannot be predicted, as the trend is mostly explained by the shorter pregnancies.https://doi.org/10.1186/s12978-024-01787-0BirthweightCaesarean sectionGestational ageLabor inductionMaternal ageObstetrical database |
| spellingShingle | László Zsirai Attila Kun Gergely Á. Visolyi Márk M. Svébis Beatrix A. Domján Ádám Tabák Birthweight trends and their explanatory factors in Hungary between 1999 and 2018: an analysis of the Hungarian Tauffer registry Reproductive Health Birthweight Caesarean section Gestational age Labor induction Maternal age Obstetrical database |
| title | Birthweight trends and their explanatory factors in Hungary between 1999 and 2018: an analysis of the Hungarian Tauffer registry |
| title_full | Birthweight trends and their explanatory factors in Hungary between 1999 and 2018: an analysis of the Hungarian Tauffer registry |
| title_fullStr | Birthweight trends and their explanatory factors in Hungary between 1999 and 2018: an analysis of the Hungarian Tauffer registry |
| title_full_unstemmed | Birthweight trends and their explanatory factors in Hungary between 1999 and 2018: an analysis of the Hungarian Tauffer registry |
| title_short | Birthweight trends and their explanatory factors in Hungary between 1999 and 2018: an analysis of the Hungarian Tauffer registry |
| title_sort | birthweight trends and their explanatory factors in hungary between 1999 and 2018 an analysis of the hungarian tauffer registry |
| topic | Birthweight Caesarean section Gestational age Labor induction Maternal age Obstetrical database |
| url | https://doi.org/10.1186/s12978-024-01787-0 |
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