Bacterial origins of thymidylate metabolism in Asgard archaea and Eukarya
Asgard archaea include the closest known archaeal relatives of eukaryotes. Here, the authors provide evidence that eukaryotic and Asgard thymidylate synthases (required for DNA synthesis) may have a bacterial origin, and additional lateral transfer of bacterial genes may have shaped the metabolism o...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-36487-z |
| _version_ | 1797864081923768320 |
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| author | Jonathan Filée Hubert F. Becker Lucille Mellottee Rima Zein Eddine Zhihui Li Wenlu Yin Jean-Christophe Lambry Ursula Liebl Hannu Myllykallio |
| author_facet | Jonathan Filée Hubert F. Becker Lucille Mellottee Rima Zein Eddine Zhihui Li Wenlu Yin Jean-Christophe Lambry Ursula Liebl Hannu Myllykallio |
| author_sort | Jonathan Filée |
| collection | DOAJ |
| description | Asgard archaea include the closest known archaeal relatives of eukaryotes. Here, the authors provide evidence that eukaryotic and Asgard thymidylate synthases (required for DNA synthesis) may have a bacterial origin, and additional lateral transfer of bacterial genes may have shaped the metabolism of Asgard archaea. |
| first_indexed | 2024-04-09T22:46:55Z |
| format | Article |
| id | doaj.art-5a94de8dfcf84a1fa8bead9006dbbaad |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-09T22:46:55Z |
| publishDate | 2023-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-5a94de8dfcf84a1fa8bead9006dbbaad2023-03-22T11:48:38ZengNature PortfolioNature Communications2041-17232023-02-0114111510.1038/s41467-023-36487-zBacterial origins of thymidylate metabolism in Asgard archaea and EukaryaJonathan Filée0Hubert F. Becker1Lucille Mellottee2Rima Zein Eddine3Zhihui Li4Wenlu Yin5Jean-Christophe Lambry6Ursula Liebl7Hannu Myllykallio8Évolution, Génomes, Comportement et Écologie, CNRS, IRD, Université Paris-SaclayLaboratoire d’Optique et Biosciences (CNRS UMR7645, INSERM U1182), Ecole Polytechnique, Institut polytechnique de ParisLaboratoire d’Optique et Biosciences (CNRS UMR7645, INSERM U1182), Ecole Polytechnique, Institut polytechnique de ParisLaboratoire d’Optique et Biosciences (CNRS UMR7645, INSERM U1182), Ecole Polytechnique, Institut polytechnique de ParisLaboratoire d’Optique et Biosciences (CNRS UMR7645, INSERM U1182), Ecole Polytechnique, Institut polytechnique de ParisLaboratoire d’Optique et Biosciences (CNRS UMR7645, INSERM U1182), Ecole Polytechnique, Institut polytechnique de ParisLaboratoire d’Optique et Biosciences (CNRS UMR7645, INSERM U1182), Ecole Polytechnique, Institut polytechnique de ParisLaboratoire d’Optique et Biosciences (CNRS UMR7645, INSERM U1182), Ecole Polytechnique, Institut polytechnique de ParisLaboratoire d’Optique et Biosciences (CNRS UMR7645, INSERM U1182), Ecole Polytechnique, Institut polytechnique de ParisAsgard archaea include the closest known archaeal relatives of eukaryotes. Here, the authors provide evidence that eukaryotic and Asgard thymidylate synthases (required for DNA synthesis) may have a bacterial origin, and additional lateral transfer of bacterial genes may have shaped the metabolism of Asgard archaea.https://doi.org/10.1038/s41467-023-36487-z |
| spellingShingle | Jonathan Filée Hubert F. Becker Lucille Mellottee Rima Zein Eddine Zhihui Li Wenlu Yin Jean-Christophe Lambry Ursula Liebl Hannu Myllykallio Bacterial origins of thymidylate metabolism in Asgard archaea and Eukarya Nature Communications |
| title | Bacterial origins of thymidylate metabolism in Asgard archaea and Eukarya |
| title_full | Bacterial origins of thymidylate metabolism in Asgard archaea and Eukarya |
| title_fullStr | Bacterial origins of thymidylate metabolism in Asgard archaea and Eukarya |
| title_full_unstemmed | Bacterial origins of thymidylate metabolism in Asgard archaea and Eukarya |
| title_short | Bacterial origins of thymidylate metabolism in Asgard archaea and Eukarya |
| title_sort | bacterial origins of thymidylate metabolism in asgard archaea and eukarya |
| url | https://doi.org/10.1038/s41467-023-36487-z |
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