Cellular Models for Primary CoQ Deficiency Pathogenesis Study

Cellular Models for Primary CoQ Deficiency Pathogenesis Study

Primary coenzyme Q<sub>10</sub> (CoQ) deficiency includes a heterogeneous group of mitochondrial diseases characterized by low mitochondrial levels of CoQ due to decreased endogenous biosynthesis rate. These diseases respond to CoQ treatment mainly at the early stages of the disease. The...

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Bibliographic Details
Main Authors: Carlos Santos-Ocaña, María V. Cascajo, María Alcázar-Fabra, Carmine Staiano, Guillermo López-Lluch, Gloria Brea-Calvo, Plácido Navas
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
coenzyme Q
coenzyme Q deficiency
mitochondrial diseases
cell models
yeast
iPSC
Online Access:https://www.mdpi.com/1422-0067/22/19/10211

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