Client proximity enhancement inside cellular membrane-less compartments governed by client-compartment interactions

Membrane-less organelles or compartments are considered to be dynamic reaction centers for spatiotemporal control of diverse cellular processes. Here authors report quantitative measurements of changes in protein interactions for the proteins recruited into membrane-less compartments (termed client...

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Main Authors: Daesun Song, Yongsang Jo, Jeong-Mo Choi, Yongwon Jung
Format: Article
Language:English
Published: Nature Portfolio 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19476-4
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author Daesun Song
Yongsang Jo
Jeong-Mo Choi
Yongwon Jung
author_facet Daesun Song
Yongsang Jo
Jeong-Mo Choi
Yongwon Jung
author_sort Daesun Song
collection DOAJ
description Membrane-less organelles or compartments are considered to be dynamic reaction centers for spatiotemporal control of diverse cellular processes. Here authors report quantitative measurements of changes in protein interactions for the proteins recruited into membrane-less compartments (termed client proteins) in living cells.
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spelling doaj.art-5a9a5c051e5e4d2f9bf037be943fedc22022-12-21T23:38:29ZengNature PortfolioNature Communications2041-17232020-11-0111111310.1038/s41467-020-19476-4Client proximity enhancement inside cellular membrane-less compartments governed by client-compartment interactionsDaesun Song0Yongsang Jo1Jeong-Mo Choi2Yongwon Jung3Department of Chemistry, Korea Advanced Institute of Science and TechnologyDepartment of Chemistry, Korea Advanced Institute of Science and TechnologyNatural Science Research Institute, Korea Advanced Institute of Science and TechnologyDepartment of Chemistry, Korea Advanced Institute of Science and TechnologyMembrane-less organelles or compartments are considered to be dynamic reaction centers for spatiotemporal control of diverse cellular processes. Here authors report quantitative measurements of changes in protein interactions for the proteins recruited into membrane-less compartments (termed client proteins) in living cells.https://doi.org/10.1038/s41467-020-19476-4
spellingShingle Daesun Song
Yongsang Jo
Jeong-Mo Choi
Yongwon Jung
Client proximity enhancement inside cellular membrane-less compartments governed by client-compartment interactions
Nature Communications
title Client proximity enhancement inside cellular membrane-less compartments governed by client-compartment interactions
title_full Client proximity enhancement inside cellular membrane-less compartments governed by client-compartment interactions
title_fullStr Client proximity enhancement inside cellular membrane-less compartments governed by client-compartment interactions
title_full_unstemmed Client proximity enhancement inside cellular membrane-less compartments governed by client-compartment interactions
title_short Client proximity enhancement inside cellular membrane-less compartments governed by client-compartment interactions
title_sort client proximity enhancement inside cellular membrane less compartments governed by client compartment interactions
url https://doi.org/10.1038/s41467-020-19476-4
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AT jeongmochoi clientproximityenhancementinsidecellularmembranelesscompartmentsgovernedbyclientcompartmentinteractions
AT yongwonjung clientproximityenhancementinsidecellularmembranelesscompartmentsgovernedbyclientcompartmentinteractions