Hyperlipidemic hypersensitivity to lethal microbial inflammation and its reversal by selective targeting of nuclear transport shuttles
Abstract Hyperlipidemia, the hallmark of Metabolic Syndrome that afflicts millions of people worldwide, exacerbates life-threatening infections. We present a new evidence for the mechanism of hyperlipidemic hypersensitivity to microbial inflammation caused by pathogen-derived inducer, LPS. We demons...
Main Authors: | Yan Liu, Jozef Zienkiewicz, Kelli L. Boyd, Taylor E. Smith, Zhi-Qi Xu, Jacek Hawiger |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-91395-w |
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