Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca2+ Pump PMCA4b and Inhibits the Migration of Melanoma Cells Independent of ERK
Several new therapeutic options emerged recently to treat metastatic melanoma; however, the high frequency of intrinsic and acquired resistance among patients shows a need for new therapeutic options. Previously, we identified the plasma membrane Ca2+ ATPase 4b (PMCA4b) as a metastasis suppressor in...
Main Authors: | Luca Hegedüs, Rita Padányi, Judit Molnár, Katalin Pászty, Karolina Varga, István Kenessey, Eszter Sárközy, Matthias Wolf, Michael Grusch, Zoltán Hegyi, László Homolya, Clemens Aigner, Tamás Garay, Balázs Hegedüs, József Tímár, Enikö Kállay, Ágnes Enyedi |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-05-01
|
Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fonc.2017.00095/full |
Similar Items
-
Ca<sup>2+</sup> Homeostasis by Plasma Membrane Ca<sup>2+</sup> ATPase (PMCA) 1 Is Essential for the Development of DP Thymocytes
by: David Beckmann, et al.
Published: (2023-01-01) -
The Plasma Membrane Ca<sup>2+</sup> Pump PMCA4b Regulates Melanoma Cell Migration through Remodeling of the Actin Cytoskeleton
by: Randa Naffa, et al.
Published: (2021-03-01) -
P38 MAPK Promotes Migration and Metastatic Activity of BRAF Mutant Melanoma Cells by Inducing Degradation of PMCA4b
by: Randa Naffa, et al.
Published: (2020-05-01) -
Inter- and intra-species conversion efficacies of Norwegian prion isolates estimated by serial protein misfolding cyclic amplification
by: Erez Harpaz, et al.
Published: (2023-09-01) -
Modulation of the Human Erythroid Plasma Membrane Calcium Pump (PMCA4b) Expression by Polymorphic Genetic Variants
by: Orsolya Mózner, et al.
Published: (2021-07-01)