The influence of fibrillin‐1 and physical activity upon tendon tissue morphology and mechanical properties in mice

The influence of fibrillin‐1 and physical activity upon tendon tissue morphology and mechanical properties in mice

Abstract Fibrillin‐1 mutations cause pathological changes in connective tissue that constitute the complex phenotype of Marfan syndrome. In this study, we used fibrillin‐1 hypomorphic and haploinsufficient mice (Fbn1mgr/mgR and Fbn1+/− mice, respectively) to investigate the impact of fibrillin‐1 def...

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Main Authors: Peter H. T. Tran, Tanja Skrba, Elisabeth Wondimu, Giuseppina Galatioto, René Brüggebusch Svensson, Annesofie T. Olesen, Abigail L. Mackey, S. Peter Magnusson, Francesco Ramirez, Michael Kjaer
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:Physiological Reports
Subjects:
Tendinopathy
Exercise
Marfan
Survival
Biomechanics
Online Access:https://doi.org/10.14814/phy2.14267

Internet

https://doi.org/10.14814/phy2.14267

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