Chromosomal instability in untreated primary prostate cancer as an indicator of metastatic potential

Chromosomal instability in untreated primary prostate cancer as an indicator of metastatic potential

Abstract Background Metastatic prostate cancer (PC) is highly lethal. The ability to identify primary tumors capable of dissemination is an unmet need in the quest to understand lethal biology and improve patient outcomes. Previous studies have linked chromosomal instability (CIN), which generates a...

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Bibliographic Details
Main Authors: Eric T. Miller, Sungyong You, Radu M. Cadaneanu, Minhyung Kim, Junhee Yoon, Sandy T. Liu, Xinmin Li, Lorna Kwan, Jennelle Hodge, Michael J. Quist, Catherine S. Grasso, Michael S. Lewis, Beatrice S. Knudsen, Michael R. Freeman, Isla P. Garraway
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Cancer
Subjects:
Prostate cancer
Metastases
Chromosomal instability
CIN
Prostate needle biopsies
TCGA
Online Access:http://link.springer.com/article/10.1186/s12885-020-06817-1

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