Anatomopathology of the Superstructure of the Stapes in Patients with Otosclerosis
Abstract Introduction Otosclerosis is a disease that causes bone resorption and deposition in the auditory structures, leading to deafness. Many studies have evaluated the histopathology of the stapes footplate in this disease (osteoblasts, osteoclasts, vascular proliferation, fibroblas...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações Ltda.
2015-01-01
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| Series: | International Archives of Otorhinolaryngology |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0034-1382096 |
| _version_ | 1818406629794643968 |
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| author | Bettina Carvalho Rogerio Hamerschmidt Jose Ederaldo Telles Nicole Richter |
| author_facet | Bettina Carvalho Rogerio Hamerschmidt Jose Ederaldo Telles Nicole Richter |
| author_sort | Bettina Carvalho |
| collection | DOAJ |
| description | Abstract
Introduction Otosclerosis is a disease that causes bone resorption and deposition in the auditory structures, leading to deafness. Many studies have evaluated the histopathology of the stapes footplate in this disease (osteoblasts, osteoclasts, vascular proliferation, fibroblasts, and histiocytes), but we found no studies in the literature involving the histology of the superstructure of the stapes.
Objectives To perform an analysis under optical microscopy of histopathologic findings of the superstructure of the stapes from patients with otosclerosis.
Methods A contemporary cross-sectional cohort study of pathology analysis of superstructures of the stapes of patients with otosclerosis.
Results Fifteen superstructures of stapes in patients with otosclerosis operated in our service and four stapes of cadavers used for dissection (controls) were evaluated. No areas of bone resorption or deposition or presence of osteoclasts and osteoblasts in the superstructure of the stapes were found. However, we found in the more distal portions of the crura areas with prominent cementitious lines and woven bone, which was different than the mature trabecular bone found in the head of the stapes or in the controls.
Conclusion There were histologic changes in the superstructure of the stapes in patients with otosclerosis operated in our service. |
| first_indexed | 2024-12-14T09:14:59Z |
| format | Article |
| id | doaj.art-5aa8868918ab4dd9851897a1c86c6762 |
| institution | Directory Open Access Journal |
| issn | 1809-9777 1809-4864 |
| language | English |
| last_indexed | 2024-12-14T09:14:59Z |
| publishDate | 2015-01-01 |
| publisher | Thieme Revinter Publicações Ltda. |
| record_format | Article |
| series | International Archives of Otorhinolaryngology |
| spelling | doaj.art-5aa8868918ab4dd9851897a1c86c67622022-12-21T23:08:29ZengThieme Revinter Publicações Ltda.International Archives of Otorhinolaryngology1809-97771809-48642015-01-01190100100410.1055/s-0034-1382096Anatomopathology of the Superstructure of the Stapes in Patients with OtosclerosisBettina Carvalho0Rogerio Hamerschmidt1Jose Ederaldo Telles2Nicole Richter3Department of ENT, IPO, Curitiba, PR, BrazilDepartment of ENT, IPO, Curitiba, PR, BrazilDepartment of Pathology, HC/UFPR, Curitiba, PR, BrazilDepartment of Pathology, IPO, Curitiba, PR, BrazilAbstract Introduction Otosclerosis is a disease that causes bone resorption and deposition in the auditory structures, leading to deafness. Many studies have evaluated the histopathology of the stapes footplate in this disease (osteoblasts, osteoclasts, vascular proliferation, fibroblasts, and histiocytes), but we found no studies in the literature involving the histology of the superstructure of the stapes. Objectives To perform an analysis under optical microscopy of histopathologic findings of the superstructure of the stapes from patients with otosclerosis. Methods A contemporary cross-sectional cohort study of pathology analysis of superstructures of the stapes of patients with otosclerosis. Results Fifteen superstructures of stapes in patients with otosclerosis operated in our service and four stapes of cadavers used for dissection (controls) were evaluated. No areas of bone resorption or deposition or presence of osteoclasts and osteoblasts in the superstructure of the stapes were found. However, we found in the more distal portions of the crura areas with prominent cementitious lines and woven bone, which was different than the mature trabecular bone found in the head of the stapes or in the controls. Conclusion There were histologic changes in the superstructure of the stapes in patients with otosclerosis operated in our service.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0034-1382096otosclerosisdeafnessstapes |
| spellingShingle | Bettina Carvalho Rogerio Hamerschmidt Jose Ederaldo Telles Nicole Richter Anatomopathology of the Superstructure of the Stapes in Patients with Otosclerosis International Archives of Otorhinolaryngology otosclerosis deafness stapes |
| title | Anatomopathology of the Superstructure of the Stapes in Patients with Otosclerosis |
| title_full | Anatomopathology of the Superstructure of the Stapes in Patients with Otosclerosis |
| title_fullStr | Anatomopathology of the Superstructure of the Stapes in Patients with Otosclerosis |
| title_full_unstemmed | Anatomopathology of the Superstructure of the Stapes in Patients with Otosclerosis |
| title_short | Anatomopathology of the Superstructure of the Stapes in Patients with Otosclerosis |
| title_sort | anatomopathology of the superstructure of the stapes in patients with otosclerosis |
| topic | otosclerosis deafness stapes |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0034-1382096 |
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