Neuroembryology and functional anatomy of craniofacial clefts
The master plan of all vertebrate embryos is based on neuroanatomy. The embryo can be anatomically divided into discrete units called neuromeres so that each carries unique genetic traits. Embryonic neural crest cells arising from each neuromere induce development of nerves and concomitant arteries...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical Publishers, Inc.
2009-10-01
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| Series: | Indian Journal of Plastic Surgery |
| Subjects: | |
| Online Access: | http://www.ijps.org/article.asp?issn=0970-0358;year=2009;volume=42;issue=3;spage=19;epage=34;aulast=Ewings |
| _version_ | 1818279618552004608 |
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| author | Ewings Ember Carstens Michael |
| author_facet | Ewings Ember Carstens Michael |
| author_sort | Ewings Ember |
| collection | DOAJ |
| description | The master plan of all vertebrate embryos is based on neuroanatomy. The embryo can be anatomically divided into discrete units called neuromeres so that each carries unique genetic traits. Embryonic neural crest cells arising from each neuromere induce development of nerves and concomitant arteries and support the development of specific craniofacial tissues or developmental fields. Fields are assembled upon each other in a programmed spatiotemporal order. Abnormalities in one field can affect the shape and position of developing adjacent fields. Craniofacial clefts represent states of excess or deficiency within and between specific developmental fields. The neuromeric organization of the embryo is the common denominator for understanding normal anatomy and pathology of the head and neck. Tessier′s observational cleft classification system can be redefined using neuroanatomic embryology. Reassessment of Tessier′s empiric observations demonstrates a more rational rearrangement of cleft zones, particularly near the midline. Neuromeric theory is also a means to understand and define other common craniofacial problems. Cleft palate, encephaloceles, craniosynostosis and cranial base defects may be analyzed in the same way. |
| first_indexed | 2024-12-12T23:36:12Z |
| format | Article |
| id | doaj.art-5aa959baf80d4ecf91575dc5ed4d9578 |
| institution | Directory Open Access Journal |
| issn | 0970-0358 1998-376X |
| language | English |
| last_indexed | 2024-12-12T23:36:12Z |
| publishDate | 2009-10-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | Indian Journal of Plastic Surgery |
| spelling | doaj.art-5aa959baf80d4ecf91575dc5ed4d95782022-12-22T00:07:28ZengThieme Medical Publishers, Inc.Indian Journal of Plastic Surgery0970-03581998-376X2009-10-014231934Neuroembryology and functional anatomy of craniofacial cleftsEwings EmberCarstens MichaelThe master plan of all vertebrate embryos is based on neuroanatomy. The embryo can be anatomically divided into discrete units called neuromeres so that each carries unique genetic traits. Embryonic neural crest cells arising from each neuromere induce development of nerves and concomitant arteries and support the development of specific craniofacial tissues or developmental fields. Fields are assembled upon each other in a programmed spatiotemporal order. Abnormalities in one field can affect the shape and position of developing adjacent fields. Craniofacial clefts represent states of excess or deficiency within and between specific developmental fields. The neuromeric organization of the embryo is the common denominator for understanding normal anatomy and pathology of the head and neck. Tessier′s observational cleft classification system can be redefined using neuroanatomic embryology. Reassessment of Tessier′s empiric observations demonstrates a more rational rearrangement of cleft zones, particularly near the midline. Neuromeric theory is also a means to understand and define other common craniofacial problems. Cleft palate, encephaloceles, craniosynostosis and cranial base defects may be analyzed in the same way.http://www.ijps.org/article.asp?issn=0970-0358;year=2009;volume=42;issue=3;spage=19;epage=34;aulast=EwingsCleft; Embryology; Tessier |
| spellingShingle | Ewings Ember Carstens Michael Neuroembryology and functional anatomy of craniofacial clefts Indian Journal of Plastic Surgery Cleft; Embryology; Tessier |
| title | Neuroembryology and functional anatomy of craniofacial clefts |
| title_full | Neuroembryology and functional anatomy of craniofacial clefts |
| title_fullStr | Neuroembryology and functional anatomy of craniofacial clefts |
| title_full_unstemmed | Neuroembryology and functional anatomy of craniofacial clefts |
| title_short | Neuroembryology and functional anatomy of craniofacial clefts |
| title_sort | neuroembryology and functional anatomy of craniofacial clefts |
| topic | Cleft; Embryology; Tessier |
| url | http://www.ijps.org/article.asp?issn=0970-0358;year=2009;volume=42;issue=3;spage=19;epage=34;aulast=Ewings |
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