Developmental hourglass and heterochronic shifts in fin and limb development

Developmental hourglass and heterochronic shifts in fin and limb development

How genetic changes are linked to morphological novelties and developmental constraints remains elusive. Here, we investigate genetic apparatuses that distinguish fish fins from tetrapod limbs by analyzing transcriptomes and open-chromatin regions (OCRs). Specifically, we compared mouse forelimb bud...

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Bibliographic Details
Main Authors: Koh Onimaru, Kaori Tatsumi, Chiharu Tanegashima, Mitsutaka Kadota, Osamu Nishimura, Shigehiro Kuraku
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
brown-banded bamboo shark
fin development
limb development
morphological evolution
transcriptome
ATAC-seq
Online Access:https://elifesciences.org/articles/62865

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