Evaluation of Chemotherapy Contamination Following the Implementation of Closed System Transfer Devices
This study compared the contamination of the chemotherapeutic agent cyclophosphamide between using a conventional admixing procedure and closed system transfer devices (CSTDs). Surface wipes and urine samples were collected for two weeks before and two weeks after the CSTDs were used. The surface w...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Environmental Research Institute, Chulalongkorn University
2015-02-01
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| Series: | Applied Environmental Research |
| Subjects: | |
| Online Access: | https://ph01.tci-thaijo.org/jer/index.php/aer/article/view/31072 |
| _version_ | 1797294827221549056 |
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| author | Warunsuda Sripakdee Suphat Subongkot Wannaporn Wattanawong Saroch Onlaor |
| author_facet | Warunsuda Sripakdee Suphat Subongkot Wannaporn Wattanawong Saroch Onlaor |
| author_sort | Warunsuda Sripakdee |
| collection | DOAJ |
| description |
This study compared the contamination of the chemotherapeutic agent cyclophosphamide between using a conventional admixing procedure and closed system transfer devices (CSTDs). Surface wipes and urine samples were collected for two weeks before and two weeks after the CSTDs were used. The surface wipe samples were collected from critical areas in an aseptic dispensary unit and a chemotherapy patient care unit. The urine samples were collected from healthcare workers. Contamination from cyclophosphamide in the surface wipe samples was detected in fewer areas following the implementation of CSTDs. The median cyclophospha-mide concentration in aseptic dispensary unit areas following the usage of CSTDs was significantly lower than what was detected when the conventional method (p = 0.036, Mann-Whitney’s U-test) was used. Cyclophosphamide contamination was not detected in critical areas of the patient care unit following the use of the CSTDs. This study demonstrates the potential advantages of utilizing CSTDs to reduce contamination from chemotherapeutic agents in a work setting.
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| first_indexed | 2024-03-07T21:37:31Z |
| format | Article |
| id | doaj.art-5aae2c517020428290c7508f5fe9adc2 |
| institution | Directory Open Access Journal |
| issn | 2287-075X |
| language | English |
| last_indexed | 2024-03-07T21:37:31Z |
| publishDate | 2015-02-01 |
| publisher | Environmental Research Institute, Chulalongkorn University |
| record_format | Article |
| series | Applied Environmental Research |
| spelling | doaj.art-5aae2c517020428290c7508f5fe9adc22024-02-26T10:51:00ZengEnvironmental Research Institute, Chulalongkorn UniversityApplied Environmental Research2287-075X2015-02-0137110.35762/AER.2015.37.1.7Evaluation of Chemotherapy Contamination Following the Implementation of Closed System Transfer DevicesWarunsuda Sripakdee0Suphat Subongkot1Wannaporn Wattanawong2Saroch Onlaor3Faculty of Pharmaceutical Sciences, Prince of Songkla University, Songkhla, ThailandFaculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, ThailandAseptic Dispensary Unit, Sapphasitthiprasong Hospital, Ubon Ratchathani, ThailandAseptic Dispensary Unit, Sapphasitthiprasong Hospital, Ubon Ratchathani, Thailand This study compared the contamination of the chemotherapeutic agent cyclophosphamide between using a conventional admixing procedure and closed system transfer devices (CSTDs). Surface wipes and urine samples were collected for two weeks before and two weeks after the CSTDs were used. The surface wipe samples were collected from critical areas in an aseptic dispensary unit and a chemotherapy patient care unit. The urine samples were collected from healthcare workers. Contamination from cyclophosphamide in the surface wipe samples was detected in fewer areas following the implementation of CSTDs. The median cyclophospha-mide concentration in aseptic dispensary unit areas following the usage of CSTDs was significantly lower than what was detected when the conventional method (p = 0.036, Mann-Whitney’s U-test) was used. Cyclophosphamide contamination was not detected in critical areas of the patient care unit following the use of the CSTDs. This study demonstrates the potential advantages of utilizing CSTDs to reduce contamination from chemotherapeutic agents in a work setting. https://ph01.tci-thaijo.org/jer/index.php/aer/article/view/31072Closed system transfer deviceAntineoplastic drugChemotherapeutic agentHealthcare workerContamination |
| spellingShingle | Warunsuda Sripakdee Suphat Subongkot Wannaporn Wattanawong Saroch Onlaor Evaluation of Chemotherapy Contamination Following the Implementation of Closed System Transfer Devices Applied Environmental Research Closed system transfer device Antineoplastic drug Chemotherapeutic agent Healthcare worker Contamination |
| title | Evaluation of Chemotherapy Contamination Following the Implementation of Closed System Transfer Devices |
| title_full | Evaluation of Chemotherapy Contamination Following the Implementation of Closed System Transfer Devices |
| title_fullStr | Evaluation of Chemotherapy Contamination Following the Implementation of Closed System Transfer Devices |
| title_full_unstemmed | Evaluation of Chemotherapy Contamination Following the Implementation of Closed System Transfer Devices |
| title_short | Evaluation of Chemotherapy Contamination Following the Implementation of Closed System Transfer Devices |
| title_sort | evaluation of chemotherapy contamination following the implementation of closed system transfer devices |
| topic | Closed system transfer device Antineoplastic drug Chemotherapeutic agent Healthcare worker Contamination |
| url | https://ph01.tci-thaijo.org/jer/index.php/aer/article/view/31072 |
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