PANCREATIC INVOLVEMENT IN LEPTOSPIROSIS
The research includes 84 patients with leptospirosis treated in Clinic at Infectious Diseases – Pleven. Mild course in 52,38%, moderate in 19,05%, and severe in 28,57% are established. Serum amylase level has been investigated in 37 cases. Increased rates are measured in 41,67% of mild cases (av. 27...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Peytchinski Publishing
2005-10-01
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| Series: | Journal of IMAB |
| Subjects: | |
| Online Access: | https://www.journal-imab-bg.org/statii-05/13-14str-b1-05.pdf |
| _version_ | 1797372784531210240 |
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| author | Maria Atanasova Galya I. Gancheva |
| author_facet | Maria Atanasova Galya I. Gancheva |
| author_sort | Maria Atanasova |
| collection | DOAJ |
| description | The research includes 84 patients with leptospirosis treated in Clinic at Infectious Diseases – Pleven. Mild course in 52,38%, moderate in 19,05%, and severe in 28,57% are established. Serum amylase level has been investigated in 37 cases. Increased rates are measured in 41,67% of mild cases (av. 279 U/L), in 25% of moderate cases (av. 290 U/L), and in 88,24% of severe cases(av. 937 U/L). Significant difference between serum amylase levels of mild and severe cases is established (p < 0,02). Presumably immunological mechanisms of damage by participation of interleukins (IL1, IL6, IL8) and tumor necrosis factor (TNF-β) are in the base of increased serum amylase level in leptospirosis. The functional changes of pancreas in leptospirosis are not fully clear and further research is needed. |
| first_indexed | 2024-03-08T18:39:49Z |
| format | Article |
| id | doaj.art-5aaf4c7abfe5423ba88b5e507ba0aeed |
| institution | Directory Open Access Journal |
| issn | 1312-773X |
| language | English |
| last_indexed | 2024-03-08T18:39:49Z |
| publishDate | 2005-10-01 |
| publisher | Peytchinski Publishing |
| record_format | Article |
| series | Journal of IMAB |
| spelling | doaj.art-5aaf4c7abfe5423ba88b5e507ba0aeed2023-12-29T07:52:05ZengPeytchinski PublishingJournal of IMAB1312-773X2005-10-01111131410.5272/jimab.2005111.13PANCREATIC INVOLVEMENT IN LEPTOSPIROSISMaria Atanasova0Galya I. Gancheva1https://orcid.org/0000-0003-3213-4372Department of Infectious Diseases, Epidemiology, Parasitology and Tropical Medicine, Medical University, Pleven, BulgariaDepartment of Infectious Diseases, Epidemiology, Parasitology and Tropical Medicine, Medical University, Pleven, BulgariaThe research includes 84 patients with leptospirosis treated in Clinic at Infectious Diseases – Pleven. Mild course in 52,38%, moderate in 19,05%, and severe in 28,57% are established. Serum amylase level has been investigated in 37 cases. Increased rates are measured in 41,67% of mild cases (av. 279 U/L), in 25% of moderate cases (av. 290 U/L), and in 88,24% of severe cases(av. 937 U/L). Significant difference between serum amylase levels of mild and severe cases is established (p < 0,02). Presumably immunological mechanisms of damage by participation of interleukins (IL1, IL6, IL8) and tumor necrosis factor (TNF-β) are in the base of increased serum amylase level in leptospirosis. The functional changes of pancreas in leptospirosis are not fully clear and further research is needed.https://www.journal-imab-bg.org/statii-05/13-14str-b1-05.pdfleptospirosispancreasserum amylaseinterleukins |
| spellingShingle | Maria Atanasova Galya I. Gancheva PANCREATIC INVOLVEMENT IN LEPTOSPIROSIS Journal of IMAB leptospirosis pancreas serum amylase interleukins |
| title | PANCREATIC INVOLVEMENT IN LEPTOSPIROSIS |
| title_full | PANCREATIC INVOLVEMENT IN LEPTOSPIROSIS |
| title_fullStr | PANCREATIC INVOLVEMENT IN LEPTOSPIROSIS |
| title_full_unstemmed | PANCREATIC INVOLVEMENT IN LEPTOSPIROSIS |
| title_short | PANCREATIC INVOLVEMENT IN LEPTOSPIROSIS |
| title_sort | pancreatic involvement in leptospirosis |
| topic | leptospirosis pancreas serum amylase interleukins |
| url | https://www.journal-imab-bg.org/statii-05/13-14str-b1-05.pdf |
| work_keys_str_mv | AT mariaatanasova pancreaticinvolvementinleptospirosis AT galyaigancheva pancreaticinvolvementinleptospirosis |