Assessing a Novel 3D Assay System for Drug Screening against OS Metastasis

Assessing a Novel 3D Assay System for Drug Screening against OS Metastasis

Osteosarcoma (OS) is an aggressive mesenchymal cell tumor that carries a poor long-term prognosis. Despite definitive surgery for the primary tumor and adjuvant chemotherapy, pulmonary metastasis is common and is the primary cause of morbidity. To improve outcomes for patients, we have developed and...

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Bibliographic Details
Main Authors: Natalie Koons, Nicole Amato, Scott Sauer, David Warshawsky, Dalit Barkan, Chand Khanna
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceuticals
Subjects:
osteosarcoma
metastatic endurance
small molecule inhibitors
oclacitinib
regorafenib
saracatinib
Online Access:https://www.mdpi.com/1424-8247/14/10/971

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