Osteoporosis recovery in severe anorexia nervosa: a case report
Abstract Background Osteoporosis represents a common and severe complication in patients with anorexia nervosa (AN) that normally persists despite weight restoration and the resumption of regular menses. The condition may result in significant pain, injury, and disability. Case presentation We repor...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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BMC
2019-11-01
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| Series: | Journal of Eating Disorders |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40337-019-0269-8 |
| _version_ | 1811173601278164992 |
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| author | Pratibha Anand Philip S. Mehler |
| author_facet | Pratibha Anand Philip S. Mehler |
| author_sort | Pratibha Anand |
| collection | DOAJ |
| description | Abstract Background Osteoporosis represents a common and severe complication in patients with anorexia nervosa (AN) that normally persists despite weight restoration and the resumption of regular menses. The condition may result in significant pain, injury, and disability. Case presentation We report the only published case of a complete return to normal bone density following many years of severe osteoporosis in a severely malnourished patient with AN. We describe a patient with severe and enduring AN whose osteoporosis, with resultant fractures, was completely reversed. Available patient records, imaging, and laboratory data were evaluated. Conclusions This case represents a common yet often improperly treated complication of AN. It demonstrates the potential important clinical role that targeted medicines coupled with a multifaceted supplementation and lifestyle interventions, may have for some very malnourished patients with AN. Medications, in the treatment of osteoporosis in patients with severe AN, may decrease fracture risk, enhance overall bone density, and contribute to an improved quality of life. |
| first_indexed | 2024-04-10T17:49:38Z |
| format | Article |
| id | doaj.art-5ab68790fd044ed288a924c9d3a2221c |
| institution | Directory Open Access Journal |
| issn | 2050-2974 |
| language | English |
| last_indexed | 2024-04-10T17:49:38Z |
| publishDate | 2019-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Eating Disorders |
| spelling | doaj.art-5ab68790fd044ed288a924c9d3a2221c2023-02-02T22:16:39ZengBMCJournal of Eating Disorders2050-29742019-11-01711310.1186/s40337-019-0269-8Osteoporosis recovery in severe anorexia nervosa: a case reportPratibha Anand0Philip S. Mehler1University of Colorado School of MedicineUniversity of Colorado School of MedicineAbstract Background Osteoporosis represents a common and severe complication in patients with anorexia nervosa (AN) that normally persists despite weight restoration and the resumption of regular menses. The condition may result in significant pain, injury, and disability. Case presentation We report the only published case of a complete return to normal bone density following many years of severe osteoporosis in a severely malnourished patient with AN. We describe a patient with severe and enduring AN whose osteoporosis, with resultant fractures, was completely reversed. Available patient records, imaging, and laboratory data were evaluated. Conclusions This case represents a common yet often improperly treated complication of AN. It demonstrates the potential important clinical role that targeted medicines coupled with a multifaceted supplementation and lifestyle interventions, may have for some very malnourished patients with AN. Medications, in the treatment of osteoporosis in patients with severe AN, may decrease fracture risk, enhance overall bone density, and contribute to an improved quality of life.http://link.springer.com/article/10.1186/s40337-019-0269-8Anorexia nervosaOsteoporosisTeriparatideDenosumabHormonal replacement therapySupplementation |
| spellingShingle | Pratibha Anand Philip S. Mehler Osteoporosis recovery in severe anorexia nervosa: a case report Journal of Eating Disorders Anorexia nervosa Osteoporosis Teriparatide Denosumab Hormonal replacement therapy Supplementation |
| title | Osteoporosis recovery in severe anorexia nervosa: a case report |
| title_full | Osteoporosis recovery in severe anorexia nervosa: a case report |
| title_fullStr | Osteoporosis recovery in severe anorexia nervosa: a case report |
| title_full_unstemmed | Osteoporosis recovery in severe anorexia nervosa: a case report |
| title_short | Osteoporosis recovery in severe anorexia nervosa: a case report |
| title_sort | osteoporosis recovery in severe anorexia nervosa a case report |
| topic | Anorexia nervosa Osteoporosis Teriparatide Denosumab Hormonal replacement therapy Supplementation |
| url | http://link.springer.com/article/10.1186/s40337-019-0269-8 |
| work_keys_str_mv | AT pratibhaanand osteoporosisrecoveryinsevereanorexianervosaacasereport AT philipsmehler osteoporosisrecoveryinsevereanorexianervosaacasereport |