Microbial Synthesis and Evaluation of Fungistatic Activity of 3-Butyl-3-hydroxyphthalide, the Mammalian Metabolite of 3-<i>n</i>-Butylidenephthalide

Microbial Synthesis and Evaluation of Fungistatic Activity of 3-Butyl-3-hydroxyphthalide, the Mammalian Metabolite of 3-<i>n</i>-Butylidenephthalide

Phthalides are bioactive compounds that naturally occur in the family Apiaceae. Considering their potentially versatile applications, it is desirable to determine their physical properties, activity and metabolic pathways. This study aimed to examine the utility of whole-cell biocatalysts for obtain...

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Bibliographic Details
Main Authors: Joanna Gach, Teresa Olejniczak, Piotr Krężel, Filip Boratyński
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
biotransformations
Apiaceae
bioactivity
phthalides
lipophilicity
lactones
Online Access:https://www.mdpi.com/1422-0067/22/14/7600

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