Direct Reprogramming of Adult Human Somatic Stem Cells Into Functional Neurons Using Sox2, Ascl1, and Neurog2

Direct Reprogramming of Adult Human Somatic Stem Cells Into Functional Neurons Using Sox2, Ascl1, and Neurog2

Reprogramming of somatic cells into induced pluripotent stem cells (iPS) or directly into cells from a different lineage, including neurons, has revolutionized research in regenerative medicine in recent years. Mesenchymal stem cells are good candidates for lineage reprogramming and autologous trans...

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Bibliographic Details
Main Authors: Jessica Alves de Medeiros Araújo, Markus M. Hilscher, Diego Marques-Coelho, Daiane C. F. Golbert, Deborah A. Cornelio, Silvia R. Batistuzzo de Medeiros, Richardson N. Leão, Marcos R. Costa
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
induced neurons
lineage reprogramming
human mesenchymal stem cells
umbilical cord
proneural genes
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00155/full

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