Determination of Perchlorate in Bottled Water from Italy
Perchlorate is regarded as an emerging persistent inorganic contaminant. It is widely known that perchlorate is an endocrine disruptor as it competitively inhibits iodide transport in the thyroid gland. As drinking water is the major source of human exposure to perchlorate, its occurrence in commerc...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2013-06-01
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| Series: | Water |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2073-4441/5/2/767 |
| _version_ | 1811311978759585792 |
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| author | Patrizia Iannece Oriana Motta Rossella Tedesco Maurizio Carotenuto Antonio Proto |
| author_facet | Patrizia Iannece Oriana Motta Rossella Tedesco Maurizio Carotenuto Antonio Proto |
| author_sort | Patrizia Iannece |
| collection | DOAJ |
| description | Perchlorate is regarded as an emerging persistent inorganic contaminant. It is widely known that perchlorate is an endocrine disruptor as it competitively inhibits iodide transport in the thyroid gland. As drinking water is the major source of human exposure to perchlorate, its occurrence in commercially available bottled waters purchased in different regions of Italy was investigated. Perchlorate was measured using the rapid, sensitive, and selective LC-ESI-MS/MS (liquid chromatography-electrospray tandem mass spectrometry) method by multiple reaction monitoring (MRM) of the transition 98.8→82.8, which corresponds to the loss of one oxygen atom in the perchlorate ion (ClO4−→ClO3−). The chlorine isotope ratio (35Cl/37Cl) was used as a confirmation tool. The limit of quantification (LOQ) for this method was 5 ng/L, and the recovery ranged from 94% to 108%. Perchlorate was detected in 44 of the 62 drinking waters tested, with concentrations ranging from <5 to 75 ng/L. These values are similar in magnitude to those reported in drinking water from the USA and do not pose an immediate health concern. |
| first_indexed | 2024-04-13T10:28:16Z |
| format | Article |
| id | doaj.art-5ac09eb20ffb430088ab5ed03dc3a240 |
| institution | Directory Open Access Journal |
| issn | 2073-4441 |
| language | English |
| last_indexed | 2024-04-13T10:28:16Z |
| publishDate | 2013-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Water |
| spelling | doaj.art-5ac09eb20ffb430088ab5ed03dc3a2402022-12-22T02:50:14ZengMDPI AGWater2073-44412013-06-015276777910.3390/w5020767Determination of Perchlorate in Bottled Water from ItalyPatrizia IanneceOriana MottaRossella TedescoMaurizio CarotenutoAntonio ProtoPerchlorate is regarded as an emerging persistent inorganic contaminant. It is widely known that perchlorate is an endocrine disruptor as it competitively inhibits iodide transport in the thyroid gland. As drinking water is the major source of human exposure to perchlorate, its occurrence in commercially available bottled waters purchased in different regions of Italy was investigated. Perchlorate was measured using the rapid, sensitive, and selective LC-ESI-MS/MS (liquid chromatography-electrospray tandem mass spectrometry) method by multiple reaction monitoring (MRM) of the transition 98.8→82.8, which corresponds to the loss of one oxygen atom in the perchlorate ion (ClO4−→ClO3−). The chlorine isotope ratio (35Cl/37Cl) was used as a confirmation tool. The limit of quantification (LOQ) for this method was 5 ng/L, and the recovery ranged from 94% to 108%. Perchlorate was detected in 44 of the 62 drinking waters tested, with concentrations ranging from <5 to 75 ng/L. These values are similar in magnitude to those reported in drinking water from the USA and do not pose an immediate health concern.http://www.mdpi.com/2073-4441/5/2/767perchloratedrinking waterLC-ESI–MS/MSmultiple reaction monitoring (MRM) |
| spellingShingle | Patrizia Iannece Oriana Motta Rossella Tedesco Maurizio Carotenuto Antonio Proto Determination of Perchlorate in Bottled Water from Italy Water perchlorate drinking water LC-ESI–MS/MS multiple reaction monitoring (MRM) |
| title | Determination of Perchlorate in Bottled Water from Italy |
| title_full | Determination of Perchlorate in Bottled Water from Italy |
| title_fullStr | Determination of Perchlorate in Bottled Water from Italy |
| title_full_unstemmed | Determination of Perchlorate in Bottled Water from Italy |
| title_short | Determination of Perchlorate in Bottled Water from Italy |
| title_sort | determination of perchlorate in bottled water from italy |
| topic | perchlorate drinking water LC-ESI–MS/MS multiple reaction monitoring (MRM) |
| url | http://www.mdpi.com/2073-4441/5/2/767 |
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