Incidence of Lower Extremity Amputation in Romania: A Nationwide 5-Year Cohort Study, 2015–2019
<i>Background and Objectives:</i> The primary objective of this study was to investigate the incidence of lower extremity amputations (LEAs) in a representative population from Romania, in both diabetic and non-diabetic adults, including trauma-related amputations. The secondary objectiv...
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MDPI AG
2023-06-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/59/7/1199 |
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| author | Emilia Rusu Horațiu Coman Andrada Coșoreanu Ana-Maria Militaru Horațiu-Cristian Popescu-Vâlceanu Ileana Teodoru Doina-Andrada Mihai Viviana Elian Norina Alinta Gavan Gabriela Radulian |
| author_facet | Emilia Rusu Horațiu Coman Andrada Coșoreanu Ana-Maria Militaru Horațiu-Cristian Popescu-Vâlceanu Ileana Teodoru Doina-Andrada Mihai Viviana Elian Norina Alinta Gavan Gabriela Radulian |
| author_sort | Emilia Rusu |
| collection | DOAJ |
| description | <i>Background and Objectives:</i> The primary objective of this study was to investigate the incidence of lower extremity amputations (LEAs) in a representative population from Romania, in both diabetic and non-diabetic adults, including trauma-related amputations. The secondary objective was to evaluate the trends in LEAs and the overall ratio of major-to-minor amputations. <i>Material and Methods:</i> The study was retrospective and included data from the Romanian National Hospital Discharge Records, conducted between 1 January 2015 and 31 December 2019. <i>Results:</i> The overall number of cases with LEAs was 88,102, out of which 38,590 were aterosclerosis-related LEAs, 40,499 were diabetes-related LEAs, and 9013 were trauma-related LEAs, with an ascending trend observed annually for each of these categories. Of the total non-traumatic amputations, 51.2% were in patients with diabetes. Most LEAs were in men. The total incidence increased from 80.61/100,000 in 2015 to 98.15/100,000 in 2019. <i>Conclusions:</i> Our study reported a 21% increase in total LEAs, 22.01% in non-traumatic LEAs, and 19.65% in trauma-related amputation. The minor-to-major amputation ratio increased over the study period in patients with diabetes. According to these findings, it is estimated that currently, in Romania, there is one diabetes-related amputation every hour and one non-traumatic amputation every 30 min. |
| first_indexed | 2024-03-11T00:51:44Z |
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| language | English |
| last_indexed | 2024-03-11T00:51:44Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-5ac1f0e160a44d6fa5f6117a86b259da2023-11-18T20:23:12ZengMDPI AGMedicina1010-660X1648-91442023-06-01597119910.3390/medicina59071199Incidence of Lower Extremity Amputation in Romania: A Nationwide 5-Year Cohort Study, 2015–2019Emilia Rusu0Horațiu Coman1Andrada Coșoreanu2Ana-Maria Militaru3Horațiu-Cristian Popescu-Vâlceanu4Ileana Teodoru5Doina-Andrada Mihai6Viviana Elian7Norina Alinta Gavan8Gabriela Radulian9Department of Diabetes, Nutrition and Metabolic Diseases, “Carol Davila” University of Medicine and Pharmacy, Malaxa Clinical Hospital, 030167 Bucharest, RomaniaDepartment of Vascular Surgery, Vascular Surgery Clinic, Cluj County Emergency Hospital, 400347 Cluj-Napoca, RomaniaDepartment of Diabetes, Nutrition and Metabolic Diseases, “Carol Davila” University of Medicine and Pharmacy, Malaxa Clinical Hospital, 030167 Bucharest, RomaniaDepartment of Diabetes, Nutrition and Metabolic Diseases, Malaxa Clinical Hospital, 02441 Bucharest, RomaniaDepartment of Diabetes, Nutrition and Metabolic Diseases, 915400 Oltenita, RomaniaDepartment of Diabetes, Nutrition and Metabolic Diseases, “Carol Davila” University of Medicine and Pharmacy, “Prof. Dr. Nicolae Paulescu” National Institute for Diabetes, Nutrition and Metabolic Diseases, 030167 Bucuresti, RomaniaDepartment of Diabetes, Nutrition and Metabolic Diseases, “Carol Davila” University of Medicine and Pharmacy, “Prof. Dr. Nicolae Paulescu” National Institute for Diabetes, Nutrition and Metabolic Diseases, 030167 Bucuresti, RomaniaDepartment of Diabetes, Nutrition and Metabolic Diseases, “Carol Davila” University of Medicine and Pharmacy, “Prof. Dr. Nicolae Paulescu” National Institute for Diabetes, Nutrition and Metabolic Diseases, 030167 Bucuresti, RomaniaWörwag Pharma Romania SRL, 400267 Cluj-Napoca, RomaniaDepartment of Diabetes, Nutrition and Metabolic Diseases, “Carol Davila” University of Medicine and Pharmacy, “Prof. Dr. Nicolae Paulescu” National Institute for Diabetes, Nutrition and Metabolic Diseases, 030167 Bucuresti, Romania<i>Background and Objectives:</i> The primary objective of this study was to investigate the incidence of lower extremity amputations (LEAs) in a representative population from Romania, in both diabetic and non-diabetic adults, including trauma-related amputations. The secondary objective was to evaluate the trends in LEAs and the overall ratio of major-to-minor amputations. <i>Material and Methods:</i> The study was retrospective and included data from the Romanian National Hospital Discharge Records, conducted between 1 January 2015 and 31 December 2019. <i>Results:</i> The overall number of cases with LEAs was 88,102, out of which 38,590 were aterosclerosis-related LEAs, 40,499 were diabetes-related LEAs, and 9013 were trauma-related LEAs, with an ascending trend observed annually for each of these categories. Of the total non-traumatic amputations, 51.2% were in patients with diabetes. Most LEAs were in men. The total incidence increased from 80.61/100,000 in 2015 to 98.15/100,000 in 2019. <i>Conclusions:</i> Our study reported a 21% increase in total LEAs, 22.01% in non-traumatic LEAs, and 19.65% in trauma-related amputation. The minor-to-major amputation ratio increased over the study period in patients with diabetes. According to these findings, it is estimated that currently, in Romania, there is one diabetes-related amputation every hour and one non-traumatic amputation every 30 min.https://www.mdpi.com/1648-9144/59/7/1199lower extremity amputations (LEAs)atherosclerosis-related LEAsdiabetes-related LEAstraumatic LEAs |
| spellingShingle | Emilia Rusu Horațiu Coman Andrada Coșoreanu Ana-Maria Militaru Horațiu-Cristian Popescu-Vâlceanu Ileana Teodoru Doina-Andrada Mihai Viviana Elian Norina Alinta Gavan Gabriela Radulian Incidence of Lower Extremity Amputation in Romania: A Nationwide 5-Year Cohort Study, 2015–2019 Medicina lower extremity amputations (LEAs) atherosclerosis-related LEAs diabetes-related LEAs traumatic LEAs |
| title | Incidence of Lower Extremity Amputation in Romania: A Nationwide 5-Year Cohort Study, 2015–2019 |
| title_full | Incidence of Lower Extremity Amputation in Romania: A Nationwide 5-Year Cohort Study, 2015–2019 |
| title_fullStr | Incidence of Lower Extremity Amputation in Romania: A Nationwide 5-Year Cohort Study, 2015–2019 |
| title_full_unstemmed | Incidence of Lower Extremity Amputation in Romania: A Nationwide 5-Year Cohort Study, 2015–2019 |
| title_short | Incidence of Lower Extremity Amputation in Romania: A Nationwide 5-Year Cohort Study, 2015–2019 |
| title_sort | incidence of lower extremity amputation in romania a nationwide 5 year cohort study 2015 2019 |
| topic | lower extremity amputations (LEAs) atherosclerosis-related LEAs diabetes-related LEAs traumatic LEAs |
| url | https://www.mdpi.com/1648-9144/59/7/1199 |
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