Olfactory marker protein contains a leucine-rich domain in the Ω-loop important for nuclear export

Olfactory marker protein contains a leucine-rich domain in the Ω-loop important for nuclear export

Abstract Olfactory marker protein (OMP) is a cytosolic protein expressed in mature olfactory receptor neurons (ORNs). OMP modulates cAMP signalling and regulates olfactory sensation and axonal targeting. OMP is a small soluble protein, and passive diffusion between nucleus and cytoplasm is expected....

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Bibliographic Details
Main Authors: Noriyuki Nakashima, Akiko Nakashima, Kie Nakashima, Makoto Takano
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Molecular Brain
Subjects:
Olfactory marker protein (OMP)
Hypothalamic neurons
Nuclear transport
Nuclear export signals (NES)
Leucine-rich sequence
Bioinformatics
Online Access:https://doi.org/10.1186/s13041-022-00973-0

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