A GABAergic Maf-expressing interneuron subset regulates the speed of locomotion in Drosophila

Spinal interneurons (IN) coordinate motoneuron activity to modulate locomotion behavior. Here, the authors characterize a subset of IN subtypes expressing the Maf transcription factor Traffic Jam (TJ) and report the distinct effects of their activation on body posture and locomotion in Drosophila la...

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Main Authors: H. Babski, T. Jovanic, C. Surel, S. Yoshikawa, M. F Zwart, J. Valmier, J. B. Thomas, J. Enriquez, P. Carroll, A. Garcès
Format: Article
Language:English
Published: Nature Portfolio 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12693-6
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author H. Babski
T. Jovanic
C. Surel
S. Yoshikawa
M. F Zwart
J. Valmier
J. B. Thomas
J. Enriquez
P. Carroll
A. Garcès
author_facet H. Babski
T. Jovanic
C. Surel
S. Yoshikawa
M. F Zwart
J. Valmier
J. B. Thomas
J. Enriquez
P. Carroll
A. Garcès
author_sort H. Babski
collection DOAJ
description Spinal interneurons (IN) coordinate motoneuron activity to modulate locomotion behavior. Here, the authors characterize a subset of IN subtypes expressing the Maf transcription factor Traffic Jam (TJ) and report the distinct effects of their activation on body posture and locomotion in Drosophila larvae.
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spelling doaj.art-5ac537137be44f5484a2d681e66067c02022-12-21T19:33:14ZengNature PortfolioNature Communications2041-17232019-10-0110111710.1038/s41467-019-12693-6A GABAergic Maf-expressing interneuron subset regulates the speed of locomotion in DrosophilaH. Babski0T. Jovanic1C. Surel2S. Yoshikawa3M. F Zwart4J. Valmier5J. B. Thomas6J. Enriquez7P. Carroll8A. Garcès9Inserm U1051, Institute for Neurosciences of Montpellier, University of MontpellierParis-Saclay Institute of Neuroscience, UMR 9717Inserm U1051, Institute for Neurosciences of Montpellier, University of MontpellierMolecular Neurobiology Laboratory, The Salk Institute for Biological StudiesSchool of Psychology and Neuroscience, University of St AndrewsInserm U1051, Institute for Neurosciences of Montpellier, University of MontpellierMolecular Neurobiology Laboratory, The Salk Institute for Biological StudiesInstitut de Génomique Fonctionnelle de Lyon (IGFL), École Normale Supérieure de Lyon and Centre National de la Recherche Scientifique (CNRS)Inserm U1051, Institute for Neurosciences of Montpellier, University of MontpellierInstitut de Génomique Fonctionnelle de Lyon (IGFL), École Normale Supérieure de Lyon and Centre National de la Recherche Scientifique (CNRS)Spinal interneurons (IN) coordinate motoneuron activity to modulate locomotion behavior. Here, the authors characterize a subset of IN subtypes expressing the Maf transcription factor Traffic Jam (TJ) and report the distinct effects of their activation on body posture and locomotion in Drosophila larvae.https://doi.org/10.1038/s41467-019-12693-6
spellingShingle H. Babski
T. Jovanic
C. Surel
S. Yoshikawa
M. F Zwart
J. Valmier
J. B. Thomas
J. Enriquez
P. Carroll
A. Garcès
A GABAergic Maf-expressing interneuron subset regulates the speed of locomotion in Drosophila
Nature Communications
title A GABAergic Maf-expressing interneuron subset regulates the speed of locomotion in Drosophila
title_full A GABAergic Maf-expressing interneuron subset regulates the speed of locomotion in Drosophila
title_fullStr A GABAergic Maf-expressing interneuron subset regulates the speed of locomotion in Drosophila
title_full_unstemmed A GABAergic Maf-expressing interneuron subset regulates the speed of locomotion in Drosophila
title_short A GABAergic Maf-expressing interneuron subset regulates the speed of locomotion in Drosophila
title_sort gabaergic maf expressing interneuron subset regulates the speed of locomotion in drosophila
url https://doi.org/10.1038/s41467-019-12693-6
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