Central Granular Cell Odontogenic Tumor: Case Report with Literature Review of Cases Reported in the Last 71 years
The central granular cell odontogenic tumor (CGCOT) is a rare, benign, slowly growing, odontogenic neoplasm. CGCOT was not considered as a distinct entity in the WHO classification reported on 2017. This study reports a rare case of CGCOT involving the right side of maxillary anterior region of a 39...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2023-03-01
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| Series: | Journal of Dentistry |
| Subjects: | |
| Online Access: | https://dentjods.sums.ac.ir/article_48856_814b54303260b1b83b77f5883540f4ba.pdf |
| _version_ | 1797870586795393024 |
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| author | Fatemeh Mashhadiabbas Sanaz Gholami Toghchi Roohollah Safarpour |
| author_facet | Fatemeh Mashhadiabbas Sanaz Gholami Toghchi Roohollah Safarpour |
| author_sort | Fatemeh Mashhadiabbas |
| collection | DOAJ |
| description | The central granular cell odontogenic tumor (CGCOT) is a rare, benign, slowly growing, odontogenic neoplasm. CGCOT was not considered as a distinct entity in the WHO classification reported on 2017. This study reports a rare case of CGCOT involving the right side of maxillary anterior region of a 39-year-old white woman. In addition, to better delineate the clinical, radiographic, histopathologic and immunohistochemical characteristics of CGCOT, a literature review of all published cases (in PubMed/ Google Scholar/ MEDLINE/Scopus) of CGCOT is provided. CGCOT is a very uncommon tumor, with only 51 reported cases in the literature. The present case is interesting regarding to its rarity for being in the maxillary anterior region, which has not been previously reported in Asia. The immunohistochemical findings of the current case and other cases in the literature review, verified the mesenchymal origin of granular cells and odontogenic nature of the epithelium islands, which can be a possible promise for placing this lesion in the future WHO odontogenic tumor classification. |
| first_indexed | 2024-04-10T00:30:52Z |
| format | Article |
| id | doaj.art-5ac9289507854690bcd4f51b0076c1f5 |
| institution | Directory Open Access Journal |
| issn | 2345-6485 2345-6418 |
| language | English |
| last_indexed | 2024-04-10T00:30:52Z |
| publishDate | 2023-03-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Journal of Dentistry |
| spelling | doaj.art-5ac9289507854690bcd4f51b0076c1f52023-03-15T04:11:32ZengShiraz University of Medical SciencesJournal of Dentistry2345-64852345-64182023-03-0124Supplement-March-202316016710.30476/dentjods.2022.94300.177448856Central Granular Cell Odontogenic Tumor: Case Report with Literature Review of Cases Reported in the Last 71 yearsFatemeh Mashhadiabbas0Sanaz Gholami Toghchi1Roohollah Safarpour2Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Lorestan University of Medical Sciences, Khorramabad, Iran.The central granular cell odontogenic tumor (CGCOT) is a rare, benign, slowly growing, odontogenic neoplasm. CGCOT was not considered as a distinct entity in the WHO classification reported on 2017. This study reports a rare case of CGCOT involving the right side of maxillary anterior region of a 39-year-old white woman. In addition, to better delineate the clinical, radiographic, histopathologic and immunohistochemical characteristics of CGCOT, a literature review of all published cases (in PubMed/ Google Scholar/ MEDLINE/Scopus) of CGCOT is provided. CGCOT is a very uncommon tumor, with only 51 reported cases in the literature. The present case is interesting regarding to its rarity for being in the maxillary anterior region, which has not been previously reported in Asia. The immunohistochemical findings of the current case and other cases in the literature review, verified the mesenchymal origin of granular cells and odontogenic nature of the epithelium islands, which can be a possible promise for placing this lesion in the future WHO odontogenic tumor classification.https://dentjods.sums.ac.ir/article_48856_814b54303260b1b83b77f5883540f4ba.pdfcentral granular cell odontogenic tumorcentral granular cell odontogenic fibromaodontogenic tumorgranular cell ameloblastic fibroma |
| spellingShingle | Fatemeh Mashhadiabbas Sanaz Gholami Toghchi Roohollah Safarpour Central Granular Cell Odontogenic Tumor: Case Report with Literature Review of Cases Reported in the Last 71 years Journal of Dentistry central granular cell odontogenic tumor central granular cell odontogenic fibroma odontogenic tumor granular cell ameloblastic fibroma |
| title | Central Granular Cell Odontogenic Tumor: Case Report with Literature Review of Cases Reported in the Last 71 years |
| title_full | Central Granular Cell Odontogenic Tumor: Case Report with Literature Review of Cases Reported in the Last 71 years |
| title_fullStr | Central Granular Cell Odontogenic Tumor: Case Report with Literature Review of Cases Reported in the Last 71 years |
| title_full_unstemmed | Central Granular Cell Odontogenic Tumor: Case Report with Literature Review of Cases Reported in the Last 71 years |
| title_short | Central Granular Cell Odontogenic Tumor: Case Report with Literature Review of Cases Reported in the Last 71 years |
| title_sort | central granular cell odontogenic tumor case report with literature review of cases reported in the last 71 years |
| topic | central granular cell odontogenic tumor central granular cell odontogenic fibroma odontogenic tumor granular cell ameloblastic fibroma |
| url | https://dentjods.sums.ac.ir/article_48856_814b54303260b1b83b77f5883540f4ba.pdf |
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