Change in the corneal material mechanical property for small incision lenticule extraction surgery
Purpose: To assess the distribution characteristics and related factors of stress-strain index (SSI) values and discuss changes in biomechanical parameters, including SSI, after small incision lenticule extraction (SMILE) surgery.Methods: This study included 253 patients who underwent SMILE (253 eye...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-02-01
|
| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1034961/full |
| _version_ | 1797902955786010624 |
|---|---|
| author | Wenjing Gao Wenjing Gao Wenjing Gao Xinheng Zhao Xinheng Zhao Xinheng Zhao Yan Wang Yan Wang Yan Wang |
| author_facet | Wenjing Gao Wenjing Gao Wenjing Gao Xinheng Zhao Xinheng Zhao Xinheng Zhao Yan Wang Yan Wang Yan Wang |
| author_sort | Wenjing Gao |
| collection | DOAJ |
| description | Purpose: To assess the distribution characteristics and related factors of stress-strain index (SSI) values and discuss changes in biomechanical parameters, including SSI, after small incision lenticule extraction (SMILE) surgery.Methods: This study included 253 patients who underwent SMILE (253 eyes). SSI and other biomechanical parameters were measured using corneal visualization Scheimpflug technology before and 3 months after surgery. The data collected included SSI, central corneal thickness (CCT), and eight other dynamic corneal response parameters. The Kolmogorov–Smirnov test, Pearson and partial correlation analyses, and paired-sample t-tests were used for statistical analyses.Results: Both pre-op SSI and ΔSSI follow a normal distribution, while post-op SSI does not follow a normal distribution. The decline in SSI after SMILE surgery was not statistically significant, and the data dispersion of SSI after SMILE surgery was close to that before surgery (p > 0.05). No statistical correlation was noted between SSI values and age and pre-op CCT (all p > 0.05). However, both pre- and post-op SSI values decreased with increasing degree of myopia (all p < 0.05), and weakly correlated with preoperative intraocular pressure and biomechanically corrected intraocular pressure (all p < 0.05). Other biomechanical parameters changed significantly after surgery (all p < 0.001). After SMILE, the magnitude of the deformation at the highest concave, deformation ratio, and integral radius increased significantly (all p < 0.001), while the Ambrosio relational thickness horizontal, stiffness parameter A1, and Corvis biomechanical index decreased significantly (p < 0.001).Conclusion: SSI, which reflects essential corneal material attributes, differs from other corneal biomechanical parameters and remains stable before and after SMILE surgery, and can be used as an indicator to evaluate changes in corneal material properties after SMILE surgery. |
| first_indexed | 2024-04-10T09:25:22Z |
| format | Article |
| id | doaj.art-5aca15e8ef3c4d77b739bff87650b393 |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-04-10T09:25:22Z |
| publishDate | 2023-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-5aca15e8ef3c4d77b739bff87650b3932023-02-20T05:44:00ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852023-02-011110.3389/fbioe.2023.10349611034961Change in the corneal material mechanical property for small incision lenticule extraction surgeryWenjing Gao0Wenjing Gao1Wenjing Gao2Xinheng Zhao3Xinheng Zhao4Xinheng Zhao5Yan Wang6Yan Wang7Yan Wang8Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, ChinaTianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin Eye Hospital, Tianjin, ChinaNankai University Eye Institute, Nankai University Affiliated Eye Hospital, Nankai University, Tianjin, ChinaClinical College of Ophthalmology, Tianjin Medical University, Tianjin, ChinaTianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin Eye Hospital, Tianjin, ChinaNankai University Eye Institute, Nankai University Affiliated Eye Hospital, Nankai University, Tianjin, ChinaClinical College of Ophthalmology, Tianjin Medical University, Tianjin, ChinaTianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin Eye Hospital, Tianjin, ChinaNankai University Eye Institute, Nankai University Affiliated Eye Hospital, Nankai University, Tianjin, ChinaPurpose: To assess the distribution characteristics and related factors of stress-strain index (SSI) values and discuss changes in biomechanical parameters, including SSI, after small incision lenticule extraction (SMILE) surgery.Methods: This study included 253 patients who underwent SMILE (253 eyes). SSI and other biomechanical parameters were measured using corneal visualization Scheimpflug technology before and 3 months after surgery. The data collected included SSI, central corneal thickness (CCT), and eight other dynamic corneal response parameters. The Kolmogorov–Smirnov test, Pearson and partial correlation analyses, and paired-sample t-tests were used for statistical analyses.Results: Both pre-op SSI and ΔSSI follow a normal distribution, while post-op SSI does not follow a normal distribution. The decline in SSI after SMILE surgery was not statistically significant, and the data dispersion of SSI after SMILE surgery was close to that before surgery (p > 0.05). No statistical correlation was noted between SSI values and age and pre-op CCT (all p > 0.05). However, both pre- and post-op SSI values decreased with increasing degree of myopia (all p < 0.05), and weakly correlated with preoperative intraocular pressure and biomechanically corrected intraocular pressure (all p < 0.05). Other biomechanical parameters changed significantly after surgery (all p < 0.001). After SMILE, the magnitude of the deformation at the highest concave, deformation ratio, and integral radius increased significantly (all p < 0.001), while the Ambrosio relational thickness horizontal, stiffness parameter A1, and Corvis biomechanical index decreased significantly (p < 0.001).Conclusion: SSI, which reflects essential corneal material attributes, differs from other corneal biomechanical parameters and remains stable before and after SMILE surgery, and can be used as an indicator to evaluate changes in corneal material properties after SMILE surgery.https://www.frontiersin.org/articles/10.3389/fbioe.2023.1034961/fullstress-strain indexcorneamaterial propertybiomechanical propertysmall incision lenticule extraction surgerymyopia |
| spellingShingle | Wenjing Gao Wenjing Gao Wenjing Gao Xinheng Zhao Xinheng Zhao Xinheng Zhao Yan Wang Yan Wang Yan Wang Change in the corneal material mechanical property for small incision lenticule extraction surgery Frontiers in Bioengineering and Biotechnology stress-strain index cornea material property biomechanical property small incision lenticule extraction surgery myopia |
| title | Change in the corneal material mechanical property for small incision lenticule extraction surgery |
| title_full | Change in the corneal material mechanical property for small incision lenticule extraction surgery |
| title_fullStr | Change in the corneal material mechanical property for small incision lenticule extraction surgery |
| title_full_unstemmed | Change in the corneal material mechanical property for small incision lenticule extraction surgery |
| title_short | Change in the corneal material mechanical property for small incision lenticule extraction surgery |
| title_sort | change in the corneal material mechanical property for small incision lenticule extraction surgery |
| topic | stress-strain index cornea material property biomechanical property small incision lenticule extraction surgery myopia |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1034961/full |
| work_keys_str_mv | AT wenjinggao changeinthecornealmaterialmechanicalpropertyforsmallincisionlenticuleextractionsurgery AT wenjinggao changeinthecornealmaterialmechanicalpropertyforsmallincisionlenticuleextractionsurgery AT wenjinggao changeinthecornealmaterialmechanicalpropertyforsmallincisionlenticuleextractionsurgery AT xinhengzhao changeinthecornealmaterialmechanicalpropertyforsmallincisionlenticuleextractionsurgery AT xinhengzhao changeinthecornealmaterialmechanicalpropertyforsmallincisionlenticuleextractionsurgery AT xinhengzhao changeinthecornealmaterialmechanicalpropertyforsmallincisionlenticuleextractionsurgery AT yanwang changeinthecornealmaterialmechanicalpropertyforsmallincisionlenticuleextractionsurgery AT yanwang changeinthecornealmaterialmechanicalpropertyforsmallincisionlenticuleextractionsurgery AT yanwang changeinthecornealmaterialmechanicalpropertyforsmallincisionlenticuleextractionsurgery |