Identification of Nifurtimox and Chrysin as Anti-Influenza Virus Agents by Clinical Transcriptome Signature Reversion
The rapid development in the field of transcriptomics provides remarkable biomedical insights for drug discovery. In this study, a transcriptome signature reversal approach was conducted to identify the agents against influenza A virus (IAV) infection through dissecting gene expression changes in re...
Main Authors: | Yijing Xin, Shubing Chen, Ke Tang, You Wu, Ying Guo |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-02-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/23/4/2372 |
Similar Items
-
Benznidazole biotransformation in rat heart microsomal fraction without observable ultrastructural alterations: comparison to Nifurtimox-induced cardiac effects
by: María Montalto de Mecca, et al.
Published: (2008-09-01) -
Dipyridamole potentiated the trypanocidal effect of nifurtimox and improved the cardiac function in NMRI mice with acute chagasic myocarditis
by: Sonia Santeliz, et al. -
Estudo comparativo controlado com emprego de benznidazole, nifurtimox e placebo, na forma crônica da doença de Chagas, em uma área de campo com transmissão interrompida. I. Avaliação preliminar
by: José Rodrigues Coura, et al.
Published: (1997-04-01) -
Chagas disease treatment efficacy markers: experiences from a Phase III study with nifurtimox in children
by: Ulrike Grossmann, et al.
Published: (2023-09-01) -
Terapêutica da fase crônica da infecção experimental pelo Trypanosoma cruzi com o Benzonidazol e o Nifurtimox
by: Sonia G. Andrade, et al.
Published: (1989-09-01)