Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child
Acute pandysautonomia-associated distal esophageal spasm is a rare disease with an unclear etiology. Here, we describe a 12-year-old boy with an acute pandysautonomia-associated distal esophageal spasm who was treated using a peroral endoscopic myotomy (POEM). The patient's clinical features in...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2022.935915/full |
| _version_ | 1797951375109259264 |
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| author | Hanhua Zhang Biyun Chi Fengfan Wang Pei Shao Huanyu Liu Ying Fang |
| author_facet | Hanhua Zhang Biyun Chi Fengfan Wang Pei Shao Huanyu Liu Ying Fang |
| author_sort | Hanhua Zhang |
| collection | DOAJ |
| description | Acute pandysautonomia-associated distal esophageal spasm is a rare disease with an unclear etiology. Here, we describe a 12-year-old boy with an acute pandysautonomia-associated distal esophageal spasm who was treated using a peroral endoscopic myotomy (POEM). The patient's clinical features included recurrent dysphagia, nausea, vomiting, growth retardation, and signs of autonomic nerve dysfunction (e.g., a decreased production of tears and sweat, and an increased production of saliva). Signs of the distal esophageal spasm were visible in upper gastrointestinal radiography, endoscopy, and high-resolution esophageal manometry. After the POEM, the patient exhibited improvements in nausea and vomiting, and his dysphagia symptoms were relieved by the 6-month follow-up visit. However, the patient's neurological problems persisted. The satisfactory short-term clinical responses in our patient suggest that POEM is feasible, safe, and effective for the treatment of acute pandysautonomia-associated distal esophageal spasms in children. |
| first_indexed | 2024-04-10T22:29:36Z |
| format | Article |
| id | doaj.art-5aca7552371b43e6b7990a73277b7e37 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-10T22:29:36Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-5aca7552371b43e6b7990a73277b7e372023-01-17T06:20:41ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602023-01-011010.3389/fped.2022.935915935915Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a childHanhua Zhang0Biyun Chi1Fengfan Wang2Pei Shao3Huanyu Liu4Ying Fang5Department of Gastroenterology, Xi'an Children's Hospital, Xi ‘an, ChinaXi'an Medical University, Xi'an, ChinaDepartment of Gastroenterology, Xi'an Children's Hospital, Xi ‘an, ChinaDepartment of Gastroenterology, Xi'an Children's Hospital, Xi ‘an, ChinaDepartment of Gastroenterology, Xi'an Children's Hospital, Xi ‘an, ChinaDepartment of Gastroenterology, Xi'an Children's Hospital, Xi ‘an, ChinaAcute pandysautonomia-associated distal esophageal spasm is a rare disease with an unclear etiology. Here, we describe a 12-year-old boy with an acute pandysautonomia-associated distal esophageal spasm who was treated using a peroral endoscopic myotomy (POEM). The patient's clinical features included recurrent dysphagia, nausea, vomiting, growth retardation, and signs of autonomic nerve dysfunction (e.g., a decreased production of tears and sweat, and an increased production of saliva). Signs of the distal esophageal spasm were visible in upper gastrointestinal radiography, endoscopy, and high-resolution esophageal manometry. After the POEM, the patient exhibited improvements in nausea and vomiting, and his dysphagia symptoms were relieved by the 6-month follow-up visit. However, the patient's neurological problems persisted. The satisfactory short-term clinical responses in our patient suggest that POEM is feasible, safe, and effective for the treatment of acute pandysautonomia-associated distal esophageal spasms in children.https://www.frontiersin.org/articles/10.3389/fped.2022.935915/fullchildrenacute pandysautonomiadistal esophageal spasmPOEMrare case |
| spellingShingle | Hanhua Zhang Biyun Chi Fengfan Wang Pei Shao Huanyu Liu Ying Fang Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child Frontiers in Pediatrics children acute pandysautonomia distal esophageal spasm POEM rare case |
| title | Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child |
| title_full | Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child |
| title_fullStr | Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child |
| title_full_unstemmed | Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child |
| title_short | Case report: Peroral endoscopic myotomy for acute pandysautonomia-associated distal esophageal spasm in a child |
| title_sort | case report peroral endoscopic myotomy for acute pandysautonomia associated distal esophageal spasm in a child |
| topic | children acute pandysautonomia distal esophageal spasm POEM rare case |
| url | https://www.frontiersin.org/articles/10.3389/fped.2022.935915/full |
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