Apolipoprotein CIII Reduction Protects White Adipose Tissues against Obesity-Induced Inflammation and Insulin Resistance in Mice

Apolipoprotein CIII Reduction Protects White Adipose Tissues against Obesity-Induced Inflammation and Insulin Resistance in Mice

Apolipoprotein CIII (apoCIII) is proinflammatory and increases in high-fat diet (HFD)-induced obesity and insulin resistance. We have previously shown that reducing apoCIII improves insulin sensitivity in vivo by complex mechanisms involving liver and brown adipose tissue. In this study the focus wa...

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Bibliographic Details
Main Authors: Patricia Recio-López, Ismael Valladolid-Acebes, Per-Olof Berggren, Lisa Juntti-Berggren
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
apolipoprotein CIII
diet-induced obesity
insulin resistance
white adipose tissue
inflammation
antisense oligonucleotides
Online Access:https://www.mdpi.com/1422-0067/23/1/62

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