A transcriptomic analysis of the effects of macrophage polarization and endotoxin tolerance on the response to Salmonella

A transcriptomic analysis of the effects of macrophage polarization and endotoxin tolerance on the response to Salmonella

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Salmonella is an intracellular pathogen causing significant morbidity and mortality. Its ability to grow inside macrophages is important to virulence, and is dependent on the activation state of the macrophages. Classically activated M1 macrophages are non-permissive for Salmonella growth, while alt...

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Bibliographic Details
Main Authors: Katharine Sedivy-Haley, Travis Blimkie, Reza Falsafi, Amy Huei-Yi Lee, Robert E. W. Hancock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565388/?tool=EBI

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