Impact of Postresuscitative Endogenous Intoxication on Lipid Peroxidation Processes in the Experiment
Endogenous intoxication and free radical oxidation were studied in rats after 10-minute clinical death due to systemic circulatory arrest. There were qualitative and quantitative changes in toxic substances throughout a 35-day postresuscitative period, as well as increased free radical oxidation pro...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2006-12-01
|
| Series: | Общая реаниматология |
| Subjects: | |
| Online Access: | https://www.reanimatology.com/rmt/article/view/1370 |
| _version_ | 1826562359189045248 |
|---|---|
| author | D. A. Yenikeyev Ye. A. Nurgaleyeva A. F. Samigullina Yu. L. Baimurzina M. A. Aleksandrov |
| author_facet | D. A. Yenikeyev Ye. A. Nurgaleyeva A. F. Samigullina Yu. L. Baimurzina M. A. Aleksandrov |
| author_sort | D. A. Yenikeyev |
| collection | DOAJ |
| description | Endogenous intoxication and free radical oxidation were studied in rats after 10-minute clinical death due to systemic circulatory arrest. There were qualitative and quantitative changes in toxic substances throughout a 35-day postresuscitative period, as well as increased free radical oxidation processes in the vital organs (brain, liver, kidneys). At the same time, plasma samples showed inhibited chemiluminescence along with the elevated levels of low and medium molecular-weight substances since medium-weight molecules bound ferrous iron ions that were added to induce luminescence. The chemilu-minescence technique may serve as a rapid method for evaluating the degree of endogenous intoxication. |
| first_indexed | 2024-04-10T01:31:27Z |
| format | Article |
| id | doaj.art-5acc80b3f2134a329eb959e9a4af4ac1 |
| institution | Directory Open Access Journal |
| issn | 1813-9779 2411-7110 |
| language | English |
| last_indexed | 2025-03-14T09:46:49Z |
| publishDate | 2006-12-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj.art-5acc80b3f2134a329eb959e9a4af4ac12025-03-02T11:29:26ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102006-12-012611111410.15360/1813-9779-2006-6-111-1141370Impact of Postresuscitative Endogenous Intoxication on Lipid Peroxidation Processes in the ExperimentD. A. Yenikeyev0Ye. A. Nurgaleyeva1A. F. Samigullina2Yu. L. Baimurzina3M. A. Aleksandrov4Department of Pathophysiology, Bashkir State Medical University, UfaDepartment of Pathophysiology, Bashkir State Medical University, UfaDepartment of Pathophysiology, Bashkir State Medical University, UfaDepartment of Pathophysiology, Bashkir State Medical University, UfaDepartment of Pathophysiology, Bashkir State Medical University, UfaEndogenous intoxication and free radical oxidation were studied in rats after 10-minute clinical death due to systemic circulatory arrest. There were qualitative and quantitative changes in toxic substances throughout a 35-day postresuscitative period, as well as increased free radical oxidation processes in the vital organs (brain, liver, kidneys). At the same time, plasma samples showed inhibited chemiluminescence along with the elevated levels of low and medium molecular-weight substances since medium-weight molecules bound ferrous iron ions that were added to induce luminescence. The chemilu-minescence technique may serve as a rapid method for evaluating the degree of endogenous intoxication.https://www.reanimatology.com/rmt/article/view/1370endogenous intoxicationpostresuscitative periodchemiluminescence |
| spellingShingle | D. A. Yenikeyev Ye. A. Nurgaleyeva A. F. Samigullina Yu. L. Baimurzina M. A. Aleksandrov Impact of Postresuscitative Endogenous Intoxication on Lipid Peroxidation Processes in the Experiment Общая реаниматология endogenous intoxication postresuscitative period chemiluminescence |
| title | Impact of Postresuscitative Endogenous Intoxication on Lipid Peroxidation Processes in the Experiment |
| title_full | Impact of Postresuscitative Endogenous Intoxication on Lipid Peroxidation Processes in the Experiment |
| title_fullStr | Impact of Postresuscitative Endogenous Intoxication on Lipid Peroxidation Processes in the Experiment |
| title_full_unstemmed | Impact of Postresuscitative Endogenous Intoxication on Lipid Peroxidation Processes in the Experiment |
| title_short | Impact of Postresuscitative Endogenous Intoxication on Lipid Peroxidation Processes in the Experiment |
| title_sort | impact of postresuscitative endogenous intoxication on lipid peroxidation processes in the experiment |
| topic | endogenous intoxication postresuscitative period chemiluminescence |
| url | https://www.reanimatology.com/rmt/article/view/1370 |
| work_keys_str_mv | AT dayenikeyev impactofpostresuscitativeendogenousintoxicationonlipidperoxidationprocessesintheexperiment AT yeanurgaleyeva impactofpostresuscitativeendogenousintoxicationonlipidperoxidationprocessesintheexperiment AT afsamigullina impactofpostresuscitativeendogenousintoxicationonlipidperoxidationprocessesintheexperiment AT yulbaimurzina impactofpostresuscitativeendogenousintoxicationonlipidperoxidationprocessesintheexperiment AT maaleksandrov impactofpostresuscitativeendogenousintoxicationonlipidperoxidationprocessesintheexperiment |