Systemic Sarcoidosis Presenting in a Scar
While most forms of sarcoidosis of the skin do not require treatment, 40% of patients initially diagnosed with cutaneous sarcoidosis are found to have an asymptomatic disease involving other organ systems. It is the involvement of the lungs, heart, eyes, and nervous system which most often contribut...
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Format: | Article |
Language: | English |
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Hindawi Limited
2023-01-01
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Series: | Case Reports in Dermatological Medicine |
Online Access: | http://dx.doi.org/10.1155/2023/7751754 |
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author | Amy Xiao Lauryn M. Falcone Joseph C. English III |
author_facet | Amy Xiao Lauryn M. Falcone Joseph C. English III |
author_sort | Amy Xiao |
collection | DOAJ |
description | While most forms of sarcoidosis of the skin do not require treatment, 40% of patients initially diagnosed with cutaneous sarcoidosis are found to have an asymptomatic disease involving other organ systems. It is the involvement of the lungs, heart, eyes, and nervous system which most often contributes to morbidity/mortality. An early and accurate diagnosis of sarcoidosis is difficult because patients may be asymptomatic, initial presentations may vary, and there is no single reliable diagnostic test except biopsy. We present a case of scar sarcoidosis which led to the diagnosis of stage II pulmonary sarcoidosis in a woman in her 50s. Her scar sarcoidosis presented as well-circumscribed, reddish-brown macules surrounding an atrophic scar from a prior skin graft on the right leg. Biopsy revealed scattered, well-formed, non-necrotizing granulomas of the dermis composed of epithelioid histiocytes and multinucleated giant cells, surrounded by a sparse infiltrate of lymphocytes and histiocytes. A CT chest demonstrated extensive hilar lymphadenopathy, leading to a diagnosis of stage II pulmonary sarcoidosis with cutaneous involvement. This case illustrates the interesting presentation of scar sarcoidosis and underscores the importance of a broad differential including sarcoidosis for skin changes around scars and underscores the need for early biopsy. Prompt cutaneous diagnosis leads to earlier systemic evaluation, therapeutics, and better outcomes. |
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format | Article |
id | doaj.art-5ada9a13a5054e30a0c5e4a55f0a7a40 |
institution | Directory Open Access Journal |
issn | 2090-6471 |
language | English |
last_indexed | 2024-04-10T17:07:15Z |
publishDate | 2023-01-01 |
publisher | Hindawi Limited |
record_format | Article |
series | Case Reports in Dermatological Medicine |
spelling | doaj.art-5ada9a13a5054e30a0c5e4a55f0a7a402023-02-06T01:40:58ZengHindawi LimitedCase Reports in Dermatological Medicine2090-64712023-01-01202310.1155/2023/7751754Systemic Sarcoidosis Presenting in a ScarAmy Xiao0Lauryn M. Falcone1Joseph C. English III2School of MedicineDepartment of DermatologyDepartment of DermatologyWhile most forms of sarcoidosis of the skin do not require treatment, 40% of patients initially diagnosed with cutaneous sarcoidosis are found to have an asymptomatic disease involving other organ systems. It is the involvement of the lungs, heart, eyes, and nervous system which most often contributes to morbidity/mortality. An early and accurate diagnosis of sarcoidosis is difficult because patients may be asymptomatic, initial presentations may vary, and there is no single reliable diagnostic test except biopsy. We present a case of scar sarcoidosis which led to the diagnosis of stage II pulmonary sarcoidosis in a woman in her 50s. Her scar sarcoidosis presented as well-circumscribed, reddish-brown macules surrounding an atrophic scar from a prior skin graft on the right leg. Biopsy revealed scattered, well-formed, non-necrotizing granulomas of the dermis composed of epithelioid histiocytes and multinucleated giant cells, surrounded by a sparse infiltrate of lymphocytes and histiocytes. A CT chest demonstrated extensive hilar lymphadenopathy, leading to a diagnosis of stage II pulmonary sarcoidosis with cutaneous involvement. This case illustrates the interesting presentation of scar sarcoidosis and underscores the importance of a broad differential including sarcoidosis for skin changes around scars and underscores the need for early biopsy. Prompt cutaneous diagnosis leads to earlier systemic evaluation, therapeutics, and better outcomes.http://dx.doi.org/10.1155/2023/7751754 |
spellingShingle | Amy Xiao Lauryn M. Falcone Joseph C. English III Systemic Sarcoidosis Presenting in a Scar Case Reports in Dermatological Medicine |
title | Systemic Sarcoidosis Presenting in a Scar |
title_full | Systemic Sarcoidosis Presenting in a Scar |
title_fullStr | Systemic Sarcoidosis Presenting in a Scar |
title_full_unstemmed | Systemic Sarcoidosis Presenting in a Scar |
title_short | Systemic Sarcoidosis Presenting in a Scar |
title_sort | systemic sarcoidosis presenting in a scar |
url | http://dx.doi.org/10.1155/2023/7751754 |
work_keys_str_mv | AT amyxiao systemicsarcoidosispresentinginascar AT laurynmfalcone systemicsarcoidosispresentinginascar AT josephcenglishiii systemicsarcoidosispresentinginascar |