Identification of genetic loci affecting body mass index through interaction with multiple environmental factors using structured linear mixed model

Identification of genetic loci affecting body mass index through interaction with multiple environmental factors using structured linear mixed model

Abstract Multiple environmental factors could interact with a single genetic factor to affect disease phenotypes. We used Struct-LMM to identify genetic variants that interacted with environmental factors related to body mass index (BMI) using data from the Korea Association Resource. The following...

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Bibliographic Details
Main Authors: Hae-Un Jung, Won Jun Lee, Tae-Woong Ha, Ji-One Kang, Jihye Kim, Mi Kyung Kim, Sungho Won, Taesung Park, Ji Eun Lim, Bermseok Oh
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83684-1

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