The chromatin remodelling protein LSH/HELLS regulates the amount and distribution of DNA hydroxymethylation in the genome

The chromatin remodelling protein LSH/HELLS regulates the amount and distribution of DNA hydroxymethylation in the genome

Ten-Eleven Translocation (TET) proteins convert 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) leading to a dynamic epigenetic state of DNA that can influence transcription and chromatin organization. While TET proteins interact with complexes involved in transcriptional repression and act...

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Bibliographic Details
Main Authors: Maud De Dieuleveult, Martin Bizet, Laurence Colin, Emilie Calonne, Martin Bachman, Chao Li, Irina Stancheva, Benoit Miotto, François Fuks, Rachel Deplus
Format: Article
Language:English
Published: Taylor & Francis Group 2022-04-01
Series:Epigenetics
Subjects:
dna methylation
dna hydroxymethylation
tet
lsh
chromatin
gene expression
remodelling
Online Access:http://dx.doi.org/10.1080/15592294.2021.1917152

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