A Microfluidic DNA Sensor Based on Three-Dimensional (3D) Hierarchical MoS2/Carbon Nanotube Nanocomposites

In this work, we present a novel microfluidic biosensor for sensitive fluorescence detection of DNA based on 3D architectural MoS2/multi-walled carbon nanotube (MWCNT) nanocomposites. The proposed platform exhibits a high sensitivity, selectivity, and stability with a visible manner and operation si...

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Main Authors: Dahou Yang, Mahnoush Tayebi, Yinxi Huang, Hui Ying Yang, Ye Ai
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/16/11/1911
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author Dahou Yang
Mahnoush Tayebi
Yinxi Huang
Hui Ying Yang
Ye Ai
author_facet Dahou Yang
Mahnoush Tayebi
Yinxi Huang
Hui Ying Yang
Ye Ai
author_sort Dahou Yang
collection DOAJ
description In this work, we present a novel microfluidic biosensor for sensitive fluorescence detection of DNA based on 3D architectural MoS2/multi-walled carbon nanotube (MWCNT) nanocomposites. The proposed platform exhibits a high sensitivity, selectivity, and stability with a visible manner and operation simplicity. The excellent fluorescence quenching stability of a MoS2/MWCNT aqueous solution coupled with microfluidics will greatly simplify experimental steps and reduce time for large-scale DNA detection.
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spelling doaj.art-5ae0598089214d7fa376b464da2e6e0f2022-12-22T04:00:17ZengMDPI AGSensors1424-82202016-11-011611191110.3390/s16111911s16111911A Microfluidic DNA Sensor Based on Three-Dimensional (3D) Hierarchical MoS2/Carbon Nanotube NanocompositesDahou Yang0Mahnoush Tayebi1Yinxi Huang2Hui Ying Yang3Ye Ai4Pillar of Engineering Product Development, Singapore University of Technology and Design, Singapore 487372, SingaporePillar of Engineering Product Development, Singapore University of Technology and Design, Singapore 487372, SingaporePillar of Engineering Product Development, Singapore University of Technology and Design, Singapore 487372, SingaporePillar of Engineering Product Development, Singapore University of Technology and Design, Singapore 487372, SingaporePillar of Engineering Product Development, Singapore University of Technology and Design, Singapore 487372, SingaporeIn this work, we present a novel microfluidic biosensor for sensitive fluorescence detection of DNA based on 3D architectural MoS2/multi-walled carbon nanotube (MWCNT) nanocomposites. The proposed platform exhibits a high sensitivity, selectivity, and stability with a visible manner and operation simplicity. The excellent fluorescence quenching stability of a MoS2/MWCNT aqueous solution coupled with microfluidics will greatly simplify experimental steps and reduce time for large-scale DNA detection.http://www.mdpi.com/1424-8220/16/11/1911MoS2/MWCNT nanocompositesDNA fluorometric detectionmicrofluidic biosensing
spellingShingle Dahou Yang
Mahnoush Tayebi
Yinxi Huang
Hui Ying Yang
Ye Ai
A Microfluidic DNA Sensor Based on Three-Dimensional (3D) Hierarchical MoS2/Carbon Nanotube Nanocomposites
Sensors
MoS2/MWCNT nanocomposites
DNA fluorometric detection
microfluidic biosensing
title A Microfluidic DNA Sensor Based on Three-Dimensional (3D) Hierarchical MoS2/Carbon Nanotube Nanocomposites
title_full A Microfluidic DNA Sensor Based on Three-Dimensional (3D) Hierarchical MoS2/Carbon Nanotube Nanocomposites
title_fullStr A Microfluidic DNA Sensor Based on Three-Dimensional (3D) Hierarchical MoS2/Carbon Nanotube Nanocomposites
title_full_unstemmed A Microfluidic DNA Sensor Based on Three-Dimensional (3D) Hierarchical MoS2/Carbon Nanotube Nanocomposites
title_short A Microfluidic DNA Sensor Based on Three-Dimensional (3D) Hierarchical MoS2/Carbon Nanotube Nanocomposites
title_sort microfluidic dna sensor based on three dimensional 3d hierarchical mos2 carbon nanotube nanocomposites
topic MoS2/MWCNT nanocomposites
DNA fluorometric detection
microfluidic biosensing
url http://www.mdpi.com/1424-8220/16/11/1911
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