Determining Susceptibility and Potential Mediators of Resistance for the Novel Polymyxin Derivative, SPR206, in <i>Acinetobacter baumannii</i>

Determining Susceptibility and Potential Mediators of Resistance for the Novel Polymyxin Derivative, SPR206, in <i>Acinetobacter baumannii</i>

With the increase in carbapenem-resistant <i>A. baumannii</i> (CRAB) infections, there has been a resurgence in the use of polymyxins, specifically colistin (COL). Since the reintroduction of COL-based regimens in treating CRAB infections, several COL-resistant <i>A. baumannii</...

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Bibliographic Details
Main Authors: Jacinda C. Abdul-Mutakabbir, Nana Sakyi Opoku, Karen K. Tan, Peter Jorth, Victor Nizet, Hansel M. Fletcher, Keith S. Kaye, Michael J. Rybak
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Antibiotics
Subjects:
<i>Acinetobacter baumannii</i>
polymyxin derivative
colistin
SPR206
Online Access:https://www.mdpi.com/2079-6382/13/1/47

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