Pemphigus herpetiformis: Case report

Pemphigus herpetiformis is an autoimmune bullous disease considered an infrequent variant of pemphigus. It is characterized by clinical findings of dermatitis herpetiformis with immunopathological features of pemphigus. We report the case of a 33-year-old woman with dermatosis on the scalp, trunk an...

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Main Authors: Isabela Pérez-Prieto, Andrés Tirado-Sánchez, Leonel Fierro-Arias
Format: Article
Language:English
Published: Permanyer 2016-01-01
Series:Revista Médica del Hospital General de México
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0185106315000906
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author Isabela Pérez-Prieto
Andrés Tirado-Sánchez
Leonel Fierro-Arias
author_facet Isabela Pérez-Prieto
Andrés Tirado-Sánchez
Leonel Fierro-Arias
author_sort Isabela Pérez-Prieto
collection DOAJ
description Pemphigus herpetiformis is an autoimmune bullous disease considered an infrequent variant of pemphigus. It is characterized by clinical findings of dermatitis herpetiformis with immunopathological features of pemphigus. We report the case of a 33-year-old woman with dermatosis on the scalp, trunk and upper and lower extremities presenting as circular plaques with vesicles in a herpetiform pattern, white scale and yellowish crusts. Histopathological and direct immunofluorescence findings were compatible with pemphigus. The patient was treated with dapsone and prednisone, with significant improvement. This presentation is uncommon, and the clinical course differs from that of pemphigus vulgaris.
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spelling doaj.art-5aeacac9d60048b79af9423ba3f4c7af2022-12-21T19:18:21ZengPermanyerRevista Médica del Hospital General de México0185-10632016-01-01791172010.1016/j.hgmx.2015.09.005Pemphigus herpetiformis: Case reportIsabela Pérez-PrietoAndrés Tirado-SánchezLeonel Fierro-AriasPemphigus herpetiformis is an autoimmune bullous disease considered an infrequent variant of pemphigus. It is characterized by clinical findings of dermatitis herpetiformis with immunopathological features of pemphigus. We report the case of a 33-year-old woman with dermatosis on the scalp, trunk and upper and lower extremities presenting as circular plaques with vesicles in a herpetiform pattern, white scale and yellowish crusts. Histopathological and direct immunofluorescence findings were compatible with pemphigus. The patient was treated with dapsone and prednisone, with significant improvement. This presentation is uncommon, and the clinical course differs from that of pemphigus vulgaris.http://www.sciencedirect.com/science/article/pii/S0185106315000906Pemphigus herpetiformisPemphigusAutoimmune bullous diseaseHistopathologyDirect immunofluorescenceDapsonePrednisone
spellingShingle Isabela Pérez-Prieto
Andrés Tirado-Sánchez
Leonel Fierro-Arias
Pemphigus herpetiformis: Case report
Revista Médica del Hospital General de México
Pemphigus herpetiformis
Pemphigus
Autoimmune bullous disease
Histopathology
Direct immunofluorescence
Dapsone
Prednisone
title Pemphigus herpetiformis: Case report
title_full Pemphigus herpetiformis: Case report
title_fullStr Pemphigus herpetiformis: Case report
title_full_unstemmed Pemphigus herpetiformis: Case report
title_short Pemphigus herpetiformis: Case report
title_sort pemphigus herpetiformis case report
topic Pemphigus herpetiformis
Pemphigus
Autoimmune bullous disease
Histopathology
Direct immunofluorescence
Dapsone
Prednisone
url http://www.sciencedirect.com/science/article/pii/S0185106315000906
work_keys_str_mv AT isabelaperezprieto pemphigusherpetiformiscasereport
AT andrestiradosanchez pemphigusherpetiformiscasereport
AT leonelfierroarias pemphigusherpetiformiscasereport