Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease
Increased mean platelet volume (MPV) is associated with platelet reactivity and is a predictor of cardiovascular risk and unprovoked nervous thromboembolism. Mean platelet volume is a precise measure of platelet size. Studies have reported the use of MPV as a biomarker for predicting ischemic stroke...
Main Authors: | , |
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Format: | Article |
Language: | English |
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PAGEPress Publications
2018-01-01
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Series: | Italian Journal of Medicine |
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Online Access: | http://www.italjmed.org/index.php/ijm/article/view/918 |
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author | Henshaw Uchechi Okoroiwu Christopher Ogar Ogar |
author_facet | Henshaw Uchechi Okoroiwu Christopher Ogar Ogar |
author_sort | Henshaw Uchechi Okoroiwu |
collection | DOAJ |
description | Increased mean platelet volume (MPV) is associated with platelet reactivity and is a predictor of cardiovascular risk and unprovoked nervous thromboembolism. Mean platelet volume is a precise measure of platelet size. Studies have reported the use of MPV as a biomarker for predicting ischemic stroke in atrial fibrillation patients as well as in anticoagulant prescription and rhythm-control therapy. Moreover, MPV may predict cardiovascular event outcome following percutaneous coronary intervention in patients with coronary artery disease. MPV may predict residual platelet reactivity in dual antiplatelet therapy. Factors influencing MPV result were discussed. This review centered on the reports that MPV may be a biomarker of risk and prognosis of prevalent heart diseases. |
first_indexed | 2024-03-09T08:56:09Z |
format | Article |
id | doaj.art-5aeb1e9bd67b494d9262e043aa8fb087 |
institution | Directory Open Access Journal |
issn | 1877-9344 1877-9352 |
language | English |
last_indexed | 2024-03-09T08:56:09Z |
publishDate | 2018-01-01 |
publisher | PAGEPress Publications |
record_format | Article |
series | Italian Journal of Medicine |
spelling | doaj.art-5aeb1e9bd67b494d9262e043aa8fb0872023-12-02T12:57:10ZengPAGEPress PublicationsItalian Journal of Medicine1877-93441877-93522018-01-01121101410.4081/itjm.2018.918658Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart diseaseHenshaw Uchechi Okoroiwu0Christopher Ogar Ogar1Hematology Unit, Department of Medical Laboratory Science, University of CalabarHematology Unit, Department of Medical Laboratory Science, University of CalabarIncreased mean platelet volume (MPV) is associated with platelet reactivity and is a predictor of cardiovascular risk and unprovoked nervous thromboembolism. Mean platelet volume is a precise measure of platelet size. Studies have reported the use of MPV as a biomarker for predicting ischemic stroke in atrial fibrillation patients as well as in anticoagulant prescription and rhythm-control therapy. Moreover, MPV may predict cardiovascular event outcome following percutaneous coronary intervention in patients with coronary artery disease. MPV may predict residual platelet reactivity in dual antiplatelet therapy. Factors influencing MPV result were discussed. This review centered on the reports that MPV may be a biomarker of risk and prognosis of prevalent heart diseases.http://www.italjmed.org/index.php/ijm/article/view/918Mean platelet volumecardiovascular diseaseatrial fibrillationmyocardial infarctionbiomarker. |
spellingShingle | Henshaw Uchechi Okoroiwu Christopher Ogar Ogar Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease Italian Journal of Medicine Mean platelet volume cardiovascular disease atrial fibrillation myocardial infarction biomarker. |
title | Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease |
title_full | Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease |
title_fullStr | Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease |
title_full_unstemmed | Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease |
title_short | Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease |
title_sort | mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease |
topic | Mean platelet volume cardiovascular disease atrial fibrillation myocardial infarction biomarker. |
url | http://www.italjmed.org/index.php/ijm/article/view/918 |
work_keys_str_mv | AT henshawuchechiokoroiwu meanplateletvolumeasdiagnosticandtherapeuticmarkerofriskandprognosisofheartdisease AT christopherogarogar meanplateletvolumeasdiagnosticandtherapeuticmarkerofriskandprognosisofheartdisease |