Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease

Increased mean platelet volume (MPV) is associated with platelet reactivity and is a predictor of cardiovascular risk and unprovoked nervous thromboembolism. Mean platelet volume is a precise measure of platelet size. Studies have reported the use of MPV as a biomarker for predicting ischemic stroke...

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Main Authors: Henshaw Uchechi Okoroiwu, Christopher Ogar Ogar
Format: Article
Language:English
Published: PAGEPress Publications 2018-01-01
Series:Italian Journal of Medicine
Subjects:
Online Access:http://www.italjmed.org/index.php/ijm/article/view/918
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author Henshaw Uchechi Okoroiwu
Christopher Ogar Ogar
author_facet Henshaw Uchechi Okoroiwu
Christopher Ogar Ogar
author_sort Henshaw Uchechi Okoroiwu
collection DOAJ
description Increased mean platelet volume (MPV) is associated with platelet reactivity and is a predictor of cardiovascular risk and unprovoked nervous thromboembolism. Mean platelet volume is a precise measure of platelet size. Studies have reported the use of MPV as a biomarker for predicting ischemic stroke in atrial fibrillation patients as well as in anticoagulant prescription and rhythm-control therapy. Moreover, MPV may predict cardiovascular event outcome following percutaneous coronary intervention in patients with coronary artery disease. MPV may predict residual platelet reactivity in dual antiplatelet therapy. Factors influencing MPV result were discussed. This review centered on the reports that MPV may be a biomarker of risk and prognosis of prevalent heart diseases.
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spelling doaj.art-5aeb1e9bd67b494d9262e043aa8fb0872023-12-02T12:57:10ZengPAGEPress PublicationsItalian Journal of Medicine1877-93441877-93522018-01-01121101410.4081/itjm.2018.918658Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart diseaseHenshaw Uchechi Okoroiwu0Christopher Ogar Ogar1Hematology Unit, Department of Medical Laboratory Science, University of CalabarHematology Unit, Department of Medical Laboratory Science, University of CalabarIncreased mean platelet volume (MPV) is associated with platelet reactivity and is a predictor of cardiovascular risk and unprovoked nervous thromboembolism. Mean platelet volume is a precise measure of platelet size. Studies have reported the use of MPV as a biomarker for predicting ischemic stroke in atrial fibrillation patients as well as in anticoagulant prescription and rhythm-control therapy. Moreover, MPV may predict cardiovascular event outcome following percutaneous coronary intervention in patients with coronary artery disease. MPV may predict residual platelet reactivity in dual antiplatelet therapy. Factors influencing MPV result were discussed. This review centered on the reports that MPV may be a biomarker of risk and prognosis of prevalent heart diseases.http://www.italjmed.org/index.php/ijm/article/view/918Mean platelet volumecardiovascular diseaseatrial fibrillationmyocardial infarctionbiomarker.
spellingShingle Henshaw Uchechi Okoroiwu
Christopher Ogar Ogar
Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease
Italian Journal of Medicine
Mean platelet volume
cardiovascular disease
atrial fibrillation
myocardial infarction
biomarker.
title Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease
title_full Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease
title_fullStr Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease
title_full_unstemmed Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease
title_short Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease
title_sort mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease
topic Mean platelet volume
cardiovascular disease
atrial fibrillation
myocardial infarction
biomarker.
url http://www.italjmed.org/index.php/ijm/article/view/918
work_keys_str_mv AT henshawuchechiokoroiwu meanplateletvolumeasdiagnosticandtherapeuticmarkerofriskandprognosisofheartdisease
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