Seroprevalence of fecal-oral transmitted hepatitis A and E virus antibodies in Burkina Faso.
Hepatitis A virus (HAV) and hepatitis E virus (HEV) infections occur chiefly as a result of unhygienic conditions. The purpose of this study was to assess the seroprevalence of antibodies to both viruses in central Burkina Faso in the absence of a recorded hepatitis epidemic. Serum samples from 178...
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Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3478277?pdf=render |
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| author | Kuan Abdoulaye Traoré Hortense Rouamba Yacouba Nébié Mahamadou Sanou Alfred S Traoré Nicolas Barro Pierre Roques |
| author_facet | Kuan Abdoulaye Traoré Hortense Rouamba Yacouba Nébié Mahamadou Sanou Alfred S Traoré Nicolas Barro Pierre Roques |
| author_sort | Kuan Abdoulaye Traoré |
| collection | DOAJ |
| description | Hepatitis A virus (HAV) and hepatitis E virus (HEV) infections occur chiefly as a result of unhygienic conditions. The purpose of this study was to assess the seroprevalence of antibodies to both viruses in central Burkina Faso in the absence of a recorded hepatitis epidemic. Serum samples from 178 blood donors (131 males and 47 females) and from 189 pregnant women were collected from November 2010 to March 2012, at blood banks and medical centers in Burkina Faso. An immunochromatography test was used to screen for Anti-HAV IgM and IgG in a subgroup of 91 blood donors and 100 pregnant women. The seroprevalence of anti-HAV IgG was 14.3% [CI95, 7.1-21.4%] for all blood donors and 23% [CI95, 14.8-31.2%] for pregnant women. Anti-HEV IgG were detected using the ELISA kits Dia.pro and Wantai and were found in 19.1% [CI95, 13.3-24.9%] of the blood donors and 11.6% [CI95, 7.1-16.2%] of the pregnant women. The seroprevalences of anti-HAV and anti-HEV IgGs did not differ significantly between men and women blood donors. Anti-HAV IgM was detected in 3.3% of the blood donors and in 2% of the pregnant women. These findings for asymptomatic individuals indicate that the HAV and HEV circulate at low but significant levels. This is the first evaluation of the acute hepatitis virus burden in Burkina Faso and the underlying epidemiologic status of the population. |
| first_indexed | 2024-12-22T19:55:15Z |
| format | Article |
| id | doaj.art-5aeb3a55d76f48c0b4b2570e305e9b07 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-22T19:55:15Z |
| publishDate | 2012-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-5aeb3a55d76f48c0b4b2570e305e9b072022-12-21T18:14:26ZengPublic Library of Science (PLoS)PLoS ONE1932-62032012-01-01710e4812510.1371/journal.pone.0048125Seroprevalence of fecal-oral transmitted hepatitis A and E virus antibodies in Burkina Faso.Kuan Abdoulaye TraoréHortense RouambaYacouba NébiéMahamadou SanouAlfred S TraoréNicolas BarroPierre RoquesHepatitis A virus (HAV) and hepatitis E virus (HEV) infections occur chiefly as a result of unhygienic conditions. The purpose of this study was to assess the seroprevalence of antibodies to both viruses in central Burkina Faso in the absence of a recorded hepatitis epidemic. Serum samples from 178 blood donors (131 males and 47 females) and from 189 pregnant women were collected from November 2010 to March 2012, at blood banks and medical centers in Burkina Faso. An immunochromatography test was used to screen for Anti-HAV IgM and IgG in a subgroup of 91 blood donors and 100 pregnant women. The seroprevalence of anti-HAV IgG was 14.3% [CI95, 7.1-21.4%] for all blood donors and 23% [CI95, 14.8-31.2%] for pregnant women. Anti-HEV IgG were detected using the ELISA kits Dia.pro and Wantai and were found in 19.1% [CI95, 13.3-24.9%] of the blood donors and 11.6% [CI95, 7.1-16.2%] of the pregnant women. The seroprevalences of anti-HAV and anti-HEV IgGs did not differ significantly between men and women blood donors. Anti-HAV IgM was detected in 3.3% of the blood donors and in 2% of the pregnant women. These findings for asymptomatic individuals indicate that the HAV and HEV circulate at low but significant levels. This is the first evaluation of the acute hepatitis virus burden in Burkina Faso and the underlying epidemiologic status of the population.http://europepmc.org/articles/PMC3478277?pdf=render |
| spellingShingle | Kuan Abdoulaye Traoré Hortense Rouamba Yacouba Nébié Mahamadou Sanou Alfred S Traoré Nicolas Barro Pierre Roques Seroprevalence of fecal-oral transmitted hepatitis A and E virus antibodies in Burkina Faso. PLoS ONE |
| title | Seroprevalence of fecal-oral transmitted hepatitis A and E virus antibodies in Burkina Faso. |
| title_full | Seroprevalence of fecal-oral transmitted hepatitis A and E virus antibodies in Burkina Faso. |
| title_fullStr | Seroprevalence of fecal-oral transmitted hepatitis A and E virus antibodies in Burkina Faso. |
| title_full_unstemmed | Seroprevalence of fecal-oral transmitted hepatitis A and E virus antibodies in Burkina Faso. |
| title_short | Seroprevalence of fecal-oral transmitted hepatitis A and E virus antibodies in Burkina Faso. |
| title_sort | seroprevalence of fecal oral transmitted hepatitis a and e virus antibodies in burkina faso |
| url | http://europepmc.org/articles/PMC3478277?pdf=render |
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