Role of minimal hepatic encephalopathy in road traffic accidents
Abstract Background The term minimal hepatic encephalopathy (MHE) is defined as encephalopathy that does not lead to clinically overt cognitive dysfunction but can have an impact on quality of life, risk of involvement in road traffic accidents, and ability to function in daily life. Objective To id...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2019-01-01
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| Series: | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s41983-019-0055-1 |
| _version_ | 1818986059284873216 |
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| author | Mohammad Mohai El-Din Awad Abd-El Raouf Mohamed El-Deib Fadia Mostafa Attia Mohamed Negm Mohamed Hassan Mohamed Soliman Wafaa Hassan Omar |
| author_facet | Mohammad Mohai El-Din Awad Abd-El Raouf Mohamed El-Deib Fadia Mostafa Attia Mohamed Negm Mohamed Hassan Mohamed Soliman Wafaa Hassan Omar |
| author_sort | Mohammad Mohai El-Din Awad |
| collection | DOAJ |
| description | Abstract Background The term minimal hepatic encephalopathy (MHE) is defined as encephalopathy that does not lead to clinically overt cognitive dysfunction but can have an impact on quality of life, risk of involvement in road traffic accidents, and ability to function in daily life. Objective To identify the incidence of minimal hepatic encephalopathy in patients actively involved in a road traffic accident and its role in the increased incidence of road traffic accidents. Patients and methods We included 74 patients presented in road traffic accidents (drivers, history of fall, pedestrians whom accidents occur during crossing the road) with clinically proven hepatic cirrhosis, without clinical manifestation of hepatic encephalopathy (HE). Thorough history taking, clinical examinations, routine laboratory investigations, serum IL-6 and ammonia in blood were done. Diagnosis of MHE is based on psychometric hepatic encephalopathy score (PHES) which includes digit symbol test (DST), number connection test-A (NCT-A), number connection test-B (NCT-B), serial dotting test (SDT), and line drawing test (LDT). Results The mean age was 52.0 ± 7.47 in MHE patients. Most of the MHE patients were males. Most of the patients with MHE were working other jobs and were not drivers (63.2% vs 36.8%). MHE was observed in 19 patients (25.7%). Albumin, interleukin-6 (IL-6), and ammonia were statistically significantly different between both groups. Conclusion Minimal hepatic encephalopathy (MHE) was observed in 25.7% of patients which points that we must give attention in the screening of MHE as road traffic accident is considered the main cause of mortality in our community with high incidence of liver disease. |
| first_indexed | 2024-12-20T18:44:46Z |
| format | Article |
| id | doaj.art-5aed6d2f0d8544b7bd9ef0634b6f37cf |
| institution | Directory Open Access Journal |
| issn | 1687-8329 |
| language | English |
| last_indexed | 2024-12-20T18:44:46Z |
| publishDate | 2019-01-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery |
| spelling | doaj.art-5aed6d2f0d8544b7bd9ef0634b6f37cf2022-12-21T19:29:44ZengSpringerOpenThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery1687-83292019-01-015511710.1186/s41983-019-0055-1Role of minimal hepatic encephalopathy in road traffic accidentsMohammad Mohai El-Din Awad0Abd-El Raouf Mohamed El-Deib1Fadia Mostafa Attia2Mohamed Negm3Mohamed Hassan Mohamed Soliman4Wafaa Hassan Omar5Suez Canal UniversitySuez Canal UniversitySuez Canal UniversityFaculty of Medicine, Suez Canal UniversitySuez Canal UniversitySuez Canal UniversityAbstract Background The term minimal hepatic encephalopathy (MHE) is defined as encephalopathy that does not lead to clinically overt cognitive dysfunction but can have an impact on quality of life, risk of involvement in road traffic accidents, and ability to function in daily life. Objective To identify the incidence of minimal hepatic encephalopathy in patients actively involved in a road traffic accident and its role in the increased incidence of road traffic accidents. Patients and methods We included 74 patients presented in road traffic accidents (drivers, history of fall, pedestrians whom accidents occur during crossing the road) with clinically proven hepatic cirrhosis, without clinical manifestation of hepatic encephalopathy (HE). Thorough history taking, clinical examinations, routine laboratory investigations, serum IL-6 and ammonia in blood were done. Diagnosis of MHE is based on psychometric hepatic encephalopathy score (PHES) which includes digit symbol test (DST), number connection test-A (NCT-A), number connection test-B (NCT-B), serial dotting test (SDT), and line drawing test (LDT). Results The mean age was 52.0 ± 7.47 in MHE patients. Most of the MHE patients were males. Most of the patients with MHE were working other jobs and were not drivers (63.2% vs 36.8%). MHE was observed in 19 patients (25.7%). Albumin, interleukin-6 (IL-6), and ammonia were statistically significantly different between both groups. Conclusion Minimal hepatic encephalopathy (MHE) was observed in 25.7% of patients which points that we must give attention in the screening of MHE as road traffic accident is considered the main cause of mortality in our community with high incidence of liver disease.http://link.springer.com/article/10.1186/s41983-019-0055-1Minimal hepatic encephalopathyRoad traffic accidentsEgypt |
| spellingShingle | Mohammad Mohai El-Din Awad Abd-El Raouf Mohamed El-Deib Fadia Mostafa Attia Mohamed Negm Mohamed Hassan Mohamed Soliman Wafaa Hassan Omar Role of minimal hepatic encephalopathy in road traffic accidents The Egyptian Journal of Neurology, Psychiatry and Neurosurgery Minimal hepatic encephalopathy Road traffic accidents Egypt |
| title | Role of minimal hepatic encephalopathy in road traffic accidents |
| title_full | Role of minimal hepatic encephalopathy in road traffic accidents |
| title_fullStr | Role of minimal hepatic encephalopathy in road traffic accidents |
| title_full_unstemmed | Role of minimal hepatic encephalopathy in road traffic accidents |
| title_short | Role of minimal hepatic encephalopathy in road traffic accidents |
| title_sort | role of minimal hepatic encephalopathy in road traffic accidents |
| topic | Minimal hepatic encephalopathy Road traffic accidents Egypt |
| url | http://link.springer.com/article/10.1186/s41983-019-0055-1 |
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